Eur J Pediatr Surg 2007; 17(6): 431-432
DOI: 10.1055/s-2007-989221
Case Report

© Georg Thieme Verlag KG Stuttgart · New York

OK-432 as a Sclerosing Agent to Treat Wound-Healing Impairment

G. Fasching1 , M. Sinzig2
  • 1Department of Paediatric Surgery, General Hospital Klagenfurt, Klagenfurt, Austria
  • 2Department of Radiology, General Hospital Klagenfurt, Klagenfurt, Austria
Weitere Informationen


received May 5, 2007

accepted May 23, 2007

11. Dezember 2007 (online)


We report on the application of OK-432 (picibanil) in a patient with prolonged wound healing impairment. A 13-year-old girl had suffered a polytrauma with a displaced fracture of the sacrum which required neurosurgical decompression of the sacral plexus. Postoperatively, a seroma with recurrent fistulation was seen. Excision of the wound, prolonged suction drainage and the instillation of hypertonic glucose solution did not have any effect over a period of four months postoperatively. Relying on our personal experience of the treatment of lymphangiomas using OK-432 we instilled OK-432 into the wound. Leakage stopped immediately, there was a regression of fluid accumulation and four weeks later the ultrasound examination was normal. The patient is still asymptomatic four years after treatment. OK-432 can be used effectively for the treatment of chronic wound healing impairment.


M.D. Günter Fasching

Head, Department of Paediatric Surgery
General Hospital Klagenfurt

St. Veiter Strasse 47

9026 Klagenfurt


eMail: [email protected]