Planta Med 2007; 73(10): 1107-1111
DOI: 10.1055/s-2007-981563
Natural Product Chemistry
© Georg Thieme Verlag KG Stuttgart · New York

Flavan-3-ol-Phenylpropanoid Conjugates from Anemopaegma arvense and their Antioxidant Activities

Nurhayat Tabanca1 , Rahul S. Pawar2 , Daneel Ferreira2 , 3 , Jannie P. J. Marais2 , Shabana I. Khan2 , Vaishali Joshi2 , David E. Wedge1 , Ikhlas A. Khan2 , 3
  • 1USDA-ARS-NPURU, The University of Mississippi, University, MS, USA
  • 2National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University, MS, USA
  • 3Department of Pharmacognosy, School of Pharmacy, The University of Mississippi, University, MS, USA
Further Information

Publication History

Received: December 18, 2006 Revised: June 4, 2007

Accepted: June 8, 2007

Publication Date:
20 July 2007 (online)


One of the species of commercially available catuaba was identified as Anemopaegma arvense by comparison of its micromorphological characteristics and TLC profile with six species of authenticated plants that are commonly referred to as catuaba. The bioactivity-guided fractionation of the ethyl acetate extract of the stem bark of this catuaba sample resulted in the isolation of one new (1, catuabin A) and three known flavan-3-ol type phenylpropanoids, cinchonain Ia (2), cinchonain IIa (3), and kandelin A1 (4) with antioxidant activities. The structures of these compounds were determined by a combination of spectroscopic techniques. Additionally, these compounds were tested for their anti-inflammatory, cytotoxicity, antimalarial, and antimicrobial activities, where no activity was observed.


Ikhlas A. Khan, Ph.D

National Center for Natural Products Research

Research Institute of Pharmaceutical Sciences and Department of Pharmacognosy

School of Pharmacy

The University of Mississippi


MS 38677


Phone: +1-662-915-7821

Fax: +1-662-915-7062