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Synfacts 2007(7): 0683-0683
DOI: 10.1055/s-2007-968690
DOI: 10.1055/s-2007-968690
Synthesis of Heterocycles
© Georg Thieme Verlag Stuttgart · New York
Synthesis of Pyrazoloquinolizinones via a Three-Component Reaction
V. A. Chebanov*, V. E. Saraev, S. M. Desenko, V. N. Chernenko, S. V. Shishkina, O. V. Shishkin, K. M. Kobzar, C. O. Kappe
‘Institute for Single Crystals’ of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine; Karl-Franzens-Universität Graz, Austria; Technische Universität München, Garching, Germany
Further Information
Publication History
Publication Date:
22 June 2007 (online)
![](https://www.thieme-connect.de/media/synfacts/200707/lookinside/thumbnails/10.1055-s-2007-968690-1.jpg)
Significance
A microwave-assisted synthesis of pyrazoloquinolizinones by a 3-CR of aminopyrazoles, aldehydes and 1,3-diketones is described. The reaction, carried out under strongly basic conditions directly affords the pyrazoloquinolizinones with the stereogenic centers in trans relationship. The scope of the reaction was insufficiently explored.