Endoscopy 2007; 39: E312
DOI: 10.1055/s-2007-966831
Unusual cases and technical notes

© Georg Thieme Verlag KG Stuttgart · New York

Anisakiasis: a preventable culinary attack on the gastrointestinal tract

C.  Celestino1 , T.  Hirano2 , R.  Sáenz1 , L.  Vargas1 , J.  Gobelet1
  • 1The Latin American OMGE/OMED Advanced Gastrointestinal Endoscopy Training Center, Santiago de Chile, Chile
  • 2Center Building Clinic, Nishimachi, Iizuba, Fukuoka, Japan
Further Information

Publication History

Publication Date:
08 January 2008 (online)

A 42-year-old woman was admitted to the emergency room because of bilious vomiting and intense epigastric pain. She was unable to tolerate liquids and had moderate signs of dehydration. She had eaten raw fish (sushi) the day before. The patient was hospitalized and rehydrated. She stopped vomiting but the epigastric pain was not controlled. She underwent upper gastrointestinal endoscopy which revealed numerous erosions and ulcers in the gastric body. A parasite with the appearance of an adult Anisakis was found adherent to and penetrating the central part of an ulcer. It was withdrawn with a polypectomy snare. There was a rapid relief of symptoms. The parasitology report identified Anisakis simplex ([Fig. 1]).

Anisakiasis is related to the ingestion of raw or undercooked fish and occurs in Japanese culture (sushi, sashimi), areas in South America (“ceviche”), Spain (“vinegar anchovies”) and the Netherlands (raw fish) [1].

Anisakiasis can become a serious clinical problem when it causes gastric involvement, with ulcerations, pain and, rarely, intramural pseudotumors. Gastric involvement occurs in 90 % of cases. When upper gastrointestinal endoscopy is performed 1 or 2 days after infection, the endoscopic findings are of redness and erosions or ulcerations at the site of penetration of the gastrointestinal wall ([Fig. 2]) [2]. Steroid treatment often solves the crisis, but only expulsion of the worm or its endoscopic removal with a biopsy forceps calms the pain [3] ([Fig. 3]). The best solution to anisakiasis in humans is to prevent it by avoiding water contamination and by freezing fish that is to be eaten raw at - 20 °C for at least 5 days or at - 35 °C for 15 h.

Fig. 1 Anisakis parasite as seen by magnification endoscopy.

Fig. 2 a Anisakis parasite penetrating the gastric mucosa. b Magnification endoscopy image.

Fig. 3 The Anisakis worm was removed using a polypectomy snare.



R. Sáenz, MD

The Latin American OMGE/OMED Advanced Gastrointestinal Endoscopy Training Center Clinica Alemana-Olympus
Universidad del Desarrollo

Vitacura 5951

Fax: + 56-2-210-1478

Email: rsaenz@alemana.cl