Abstract
The pupose of this study was to determine the effects of two weeks of high dosage
iron supplementation on various blood iron indices and metabolic parameters in non-anemic,
iron-depleted competitive female crosscountry runners. The subjects were highly trained
members of the Colorado State University cross-country team and were completing 40
to 50 miles of training weekly. A pretest, post-test single-blind corssover design
was employed. Upon collection of baseline exercise blood and metabolic data, five
subjects were randomly assigned to iron supplementation (650 mg ferrous sulfate; 130
mg elemental iron) and five subjects to placebo treatment. At two weeks the treatments
were reversed. Exercise blood and metabolic data were collected at two-week intervals.
Dietary iron intake was assessed using a three-day dietary survey. Dietary analysis
revealed deficiencies in vitamin B-6, iron, magnesium, and zinc according to USRDA
standards. Baseline blood samples revealed no deficiencies in iron storage or transport
proteins. Two weeks of iron supplementation resulted in no significant increases in
blood iron indices. Metabolic parameters related to running performance were also
unchanged after iron supplementation. High dosage, short-term iron supplementation
appears to have no effect on blood or metabolic parameters in iron-depleted but non-anemic
female cross-country runners.
Key words
Ferritin - transferrin - TIBC - O2 consumption - lactate - dietary analysis - iron deficiency