Spontaneous Regression of Large-Cell Carcinoma of the Lung - a Rare Observation in Clinical Practice

F. Leo; A. G. Nicholson; D. M. Hansell; B. Corrin; U. Pastorino

doi:10.1055/s-2007-1013110

The Thoracic and Cardiovascular Surgeon, Table of Contents

Thorac Cardiovasc Surg 1999; 47(1): 53-55
DOI: 10.1055/s-2007-1013110

Case Report

Spontaneous Regression of Large-Cell Carcinoma of the Lung - a Rare Observation in Clinical Practice

F. Leo¹ , A. G. Nicholson² , D. M. Hansell³ , B. Corrin² , U. Pastorino¹

¹Thoracic Surgery Department, European Institute of Oncology, Milan, Italy
²Department of Histopathology, Royal Brompton Hospital, London, UK
³Department of Radiology, Royal Brompton Hospital, London, UK

Abstract

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Abstract

Spontaneous regression of non-small-cell lung carcinoma is extremely rare and there are few documented cases. We report a 59-year-old man with a right upper lobe tumour which showed progressive regression while hilar adenopathy appeared 2 months after the initial tumour detection. At operation, only scar tissue was found in the lung but a hilar lymphnode contained large-cell undifferentiated carcinoma. This report indicates that a decrease in size of a pulmonary mass does not exclude the diagnosis of Carcinoma and that metastatic disease canoccureven if the primary tumour regresses.

Key words

Spontaneous regression - Lung cancer - Nodal metastases - Surgery

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