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Synfacts 2006(11): 1145-1145  
DOI: 10.1055/s-2006-949451
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Biaryls via Decarboxylative Coupling

Contributor(s): Hisashi Yamamoto, Joshua P. Abell
L. J. Goossen*, G. Deng, L. M. Levy
Technische Universität Kaiserslautern, Germany
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Publikationsdatum:
24. Oktober 2006 (online)

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Significance

Biaryls are present in a large number of pharmaceutical (Boscalid) and industrial compounds (liquid crystal displays). This paper demonstrates the synthesis of the biaryl moiety without the preparation or use of expensive stoi­chiometric boronic acid derivatives.