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Synfacts 2006(11): 1087-1087  
DOI: 10.1055/s-2006-949384
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (-)-Tetrodecamycin

Contributor(s): Philip Kocienski, Thomas Snaddon
K. Tatsuta*, Y. Suzuki, A. Furuyama, H. Ikegami
Waseda University, Tokyo, Japan
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Publikationsdatum:
24. Oktober 2006 (online)

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Significance

(-)-Tetrodecamycin is a complex tetronic acid antimicrobial agent that displays activity against Pateurella piscicida, the bacteria responsible for pseudotuberculosis in fish. Noteworthy in this synthesis is the preparation of cis-diol D by a pinacol cyclization.