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Klin Monbl Augenheilkd 2006; 223(8): 643-649
DOI: 10.1055/s-2006-926784
Übersicht

© Georg Thieme Verlag KG Stuttgart · New York

Fortschritte in der Diagnose und Therapie von Erkrankungen der Augenoberfläche: Trockenes Auge und okuläre Allergien

Advances in the Diagnosis and Therapy for Diseases of the Ocular Surface: Dry Eye and Ocular AllergiesE. M. Messmer1 , J. Benitez del Castello2 , A. Lambiase3 , S. Doan4
  • 1Augenklinik der Ludwig-Maximilians-Universität, München
  • 2Hospital Clinico San Carlos, Madrid, Spanien
  • 3Campus Bio-Medico, Rom, Italien
  • 4Hôpital Bichat, Paris, Frankreich
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Publikationsverlauf

Eingegangen: 27.12.2005

Angenommen: 24.2.2006

Publikationsdatum:
22. August 2006 (online)

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Zusammenfassung

Auf dem jährlichen Treffen der „Association for Research in Vision and Ophthalmology” (ARVO) 2005 wurden neueste Forschungsergebnisse aus sämtlichen ophthalmologischen Disziplinen vorgestellt. Von besonderem Interesse war der aktuelle Forschungsstand in den Bereichen „trockenes Auge” und „okuläre Allergie”. Da diese beiden Erkrankungen häufig und aufgrund einer Reihe sich überschneidender Symptome oft schwer zu differenzieren sind, besteht Bedarf an schnelleren und genaueren Diagnosemethoden. Daher wurden zahlreiche neue Hilfsmittel vorgestellt, die in klinischen Studien, aber auch in der täglichen klinischen Praxis die Differenzialdiagnose zwischen trockenem Auge und okulärer Allergie erleichtern. Ein besseres Verständnis der molekularen Mechanismen in der Pathogenese dieser Krankheitsprozesse hat zudem zu neuen Behandlungsstrategien beim trockenen Auge und der okulären Allergie geführt.

Abstract

The 77th meeting of the Association for Research in Vision and Ophthalmology (ARVO) presented the latest developments in clinical research and practice across a range of ophthalmic disciplines. Of particular interest was the current status of research in dry eye and ocular allergy. With these conditions being very common to ophthalmologists, and the fact that they are difficult to differentiate due to the number of overlapping symptoms, there remains a need for more rapid and accurate methods for their diagnosis. Therefore, a number of new tools were presented that have the potential for use in clinical trials and practice to improve the diagnosis and assessment of dry eye and ocular allergy. Some of these tools have been developed based on a greater understanding of the pathophysiology of dry eye and ocular allergy, and the various molecular pathways involved. Indeed, a greater understanding of the molecular mechanisms involved in the pathogenesis of dry eye and ocular allergy has identified potential targets for the treatment of these conditions. Continuing research into new agents can provide ophthalmologists with a number of options that will ultimately benefit the patient.

Schlüsselwörter

Trockenes Auge - okuläre Allergie

Key words

Dry eye syndrome - ocular allergy

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Dr. Elisabeth M. Messmer

Augenklinik der Ludwig-Maximilians-Universität

Mathildenstr. 8

80336 München

Telefon: ++49/89/51 60 38 11

Fax: ++49/89/51 60 51 60

eMail: emessmer@med.uni-muenchen.de