Thorac Cardiovasc Surg 2007; 55(1): 13-18
DOI: 10.1055/s-2006-924484
Original Cardiovascular

© Georg Thieme Verlag KG Stuttgart · New York

Off-Pump versus On-Pump Coronary Artery Bypass Surgery in High-Risk Patients (EuroSCORE ≥ 6)

J. Lahtinen1 , F. Biancari1 , J. Rimpiläinen1 , R. Kytökorpi1 , M. Mosorin1 , P. Rainio1 , R. Cresti1 , T. Juvonen1 , M. Lepojärvi1
  • 1Division of Cardiothoracic and Vascular Surgery, Department of Surgery, Oulu University Hospital, Oulu, Finland
Further Information

Publication History

received April 11, 2006

Publication Date:
06 February 2007 (online)

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Abstract

Objective: The aim of this study was to review the results of off-pump (OPCAB) versus conventional on-pump coronary artery bypass surgery (CCAB) in high-risk patients. Methods: In a cohort of patients with an additive EuroSCORE ≥ 6, 67 underwent OPCAB and 112 underwent CCAB. Results: Thirty-day postoperative death and stroke rates were 7.5 % and 6.0 % for the OPCAB group, and 5.4 % (p = 0.75) and 8.0 % (p = 0.77) for the CCAB group, respectively. No significant differences were observed for other major outcome endpoints other than cardiac troponin I (OPCAB: 117 ± 428 ng/ml vs. CCAB: 58 ± 99 ng/ml, p = 0.028), a result which was probably due to preoperative massive myocardial infarction in two very high-risk patients who underwent OPCAB. A similar outcome was also observed among propensity score-matched pairs. Congestive heart failure (p = 0.006, OR: 6.366, 95 % CI: 1.682 - 24.093) and baseline cardiac index (p = 0.018, OR: 0.171, 95 % CI: 0.040 - 0.735) were independent predictors of 30-day postoperative mortality. Conclusions: OPCAB can be safely performed in high-risk patients with results as satisfactory as those achieved with CCAB.

References

MD, PhD Fausto Biancari

Division of Cardiothoracic and Vascular Surgery
Department of Surgery
Oulu University Hospital

P. O. Box 21

90029 Oulu

Finland

Phone: + 35 8 83 15 28 13

Fax: + 35 8 83 15 25 77

Email: fausto.biancari@ppshp.fi