Thorac Cardiovasc Surg 2006; 54(2): 140-142
DOI: 10.1055/s-2005-872806
Case Reports

© Georg Thieme Verlag KG Stuttgart · New York

Lepirudin for Cardiopulmonary Bypass Surgery in a Patient with Terminal Renal Insufficiency and Acute Heparin-Induced Thrombocytopenia

F.-C. Riess1 , B. Dobritzsch1 , J. Kormann1
  • 1Albertinen Heart Center, Hamburg, Germany
The work was carried out at the Albertinen Heart Center, Hamburg, Germany.
Further Information

Publication History

Received May 31, 2005

Publication Date:
15 March 2006 (online)


A patient with triple heart valve disease, heparin-induced thrombocytopenia, and terminal renal insufficiency was treated successfully using lepirudin for anticoagulation of cardiopulmonary bypass (CPB) and during the postoperative course. Anticoagulatory monitoring was performed with ecarin clotting time during CPB and aPTT postoperatively.


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