PDF herunterladen
Synfacts 2005(0): 0035-0035  
DOI: 10.1055/s-2005-869912
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
© Georg Thieme Verlag Stuttgart · New York

Ir-Catalyzed Allylic Amination and Etherification

Contributor(s): Hisashi Yamamoto, Matthew Boxer
C. Welter, A. Dahnz, B. Brunner, S. Streiff, P. Dübon, G. Helmchen*
Universität Heidelberg, Germany
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
20. Juli 2005 (online)

   Lizenzen und Reprints

Significance

This system allows for highly ste­reoselective intramolecular allylic aminations and etherifications as well as intermolecular allylic amination followed by intramolecular cyclization (shown). Low catalyst loading (2 mol%), and fast reaction times make this a suitable system for the synthesis of various ring sized N-heterocycles.