Am J Perinatol 2004; 21(5): 247-251
DOI: 10.1055/s-2004-829869
Copyright © 2004 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA.

Prenatal Diagnosis of Dilated Cavum Septum Pellucidum et Vergae

David M. Sherer1 , Margarita Sokolovski1 , Mudar Dalloul1 , Paulus Santoso1 , Janet Curcio1 , Ovadia Abulafia1
  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, State University of New York (SUNY), Downstate Medical Center, Brooklyn, New York
Further Information

Publication History

Publication Date:
01 July 2004 (online)

The cavum septum pellucidum is a fluid-filled cavity located between the membranes of the septi pellucidi, which should always be visualized sonographically in normal fetuses between 18 and 37 weeks gestation and in ∼50% of term infants. The cavum vergae, a cavity within the septum pellucidum, is located posterior to an arbitrary vertical plane formed by the columns of the fornix. We present a case in which markedly dilated cavum septum pellucidum et vergae noted at 29 weeks gestation was associated with midgut malrotation and volvulus, and review the literature pertaining to this unusual prenatal ultrasonographic diagnosis.

REFERENCES

  • 1 Loeser J D, Alvord E C. Agenesis of the corpus callosum.  Brain. 1968;  91 553-570
  • 2 Atlas S W, Zimmerman R A, Bialnuik L T et al.. Corpus callosum and limbic system: neuroanatomic MR evaluation of developmental abnormalities.  Radiology. 1986;  160 355-362
  • 3 Sarwar M. The septum pellucidum: normal and abnormal.  AJNR Am J Neuroradiol. 1989;  10 989-1005
  • 4 Jou H J, Shyu M K, Wu S C, Chen S M, Su C H, Hsieh F J. Ultrasound measurement of the fetal cavum septi pellucidi.  Ultrasound Obstet Gynecol. 1998;  12 419-422
  • 5 Falco P, Gabrielli S, Visentin A, Perolo A, Pilu G, Bovicelli L. Transabdominal sonography of the cavum septum pellucidum in normal fetuses in the second and third trimesters of pregnancy.  Ultrasound Obstet Gynecol. 2000;  16 549-553
  • 6 Mott S H, Bodensteiner J B, Allan W C. The cavum septi pellucidi in term and preterm newborn infants.  J Child Neurol. 1992;  7 35-68
  • 7 Barkovich A J, Norman D. Absence of the septum pellucidum: a useful sign in the diagnosis of congenital brain malformations.  AJR Am J Roentgenol. 1989;  152 353-360
  • 8 Bronstein M, Weiner Z. Prenatal diagnosis of dilated cava septi pellucidi et vergae: associated anomalies, differential diagnosis, and pregnancy outcome.  Obstet Gynecol. 1992;  80 838-842
  • 9 Kwon J S, Shenton M E, Hirayasu Y et al.. MRI study of cavum septum pellucidi in schizophrenia, affective disorder and schizotypal personality disorder.  Am J Psychiatry. 1998;  155 509-515
  • 10 Bodensteiner J B, Schaefer G B, Craft J M. Cavum septi pellucidi and cavum vergae in normal and developmentally delayed populations.  J Child Neurol. 1998;  13 120-121
  • 11 Nopolous P, Swayze V, Flaum M, Ehrhardt J C, Yuh W T, Andreasen N C. Cavum septi pellucidi in normals and patients with schizophrenia as detected by magnetic resonance imaging.  Biol Psychiatry. 1997;  41 1102-1108
  • 12 Delisi L E, Hoff A L, Kushner M, Degreef G. Increased prevalence of cavum septum pellucidum in schizophrenia.  Psychiatry Res. 1993;  50 193-199
  • 13 Butt W, Havill D, Daneman A, Pape K. Hemorrhage and cyst development in the cavum septi pellucidi and cavum vergae: report of three cases.  Pediatr Radiol. 1985;  15 368-371
  • 14 Boutemy R, Dan B, Christophe C, Rommens J, Perlmutter N. Hemorrhage in the cavum septi pellucidi in a full-term neonate.  Pediatr Radiol. 1997;  27 144-146
  • 15 Sahinoglu Z, Uludogan M, Delikara M N. Prenatal sonographic diagnosis of dilated cavum vergae.  J Clin Ultrasound. 2002;  30 378-383
  • 16 Vergani P, Locatelli A, Piccolo M G, Ceruti P, Patanè L, Paterlini G. Ultrasonographic differential diagnosis of fetal intracranial interhemispheric cysts.  Am J Obstet Gynecol. 1999;  180 423-428

David M ShererM.D. 

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, State University of New York (SUNY), Downstate Medical Center

450 Clarkson Avenue, Box 24

Brooklyn, NY 11203

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