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Osteosynthesis and Trauma Care 2003; 11(3): 118-121
DOI: 10.1055/s-2003-42605
Original Article

© Georg Thieme Verlag Stuttgart · New York

Results of Bone Morphogenetic Proteins in Animal Models

T. J. Blokhuis 1 , M. F. Termaat1 , F. C. Bakker1 , P. Patka1 , H. J. T. M. Haarman1
  • 1Departments of Surgery/Traumatology, VU University Medical Center, Amsterdam, The Netherlands
Further Information

Publication History

Publication Date:
29 September 2003 (online)

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Abstract

Bone morphogenetic proteins (BMPs) are capable of inducing bone formation, or osteoinduction. By now, two BMPs, BMP-7 and BMP-2, are commercially available, and have found their way into some clinical applications. In this overview, the results of several animal experiments using these two BMPs are summarized, and future directions for use of BMPs are highlighted. The focus in the described animal experiments is on fracture healing and treatment of bone defects.

Key words

Bone morphogenetic proteins (BMP) - bone healing - osteoinduction - animal models

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Taco J. Blokhuis Ph. D. 

Department of Surgery/Traumatology

VU University Medical Center

P.O. Box 70 57

1007 MB Amsterdam

The Netherlands

Phone: +31/20/4 44 02 68

Fax: +31/20/4 44 02 74

Email: tj.blokhuis@vumc.nl

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