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Pharmacopsychiatry 2002; 35(1): 31-32
DOI: 10.1055/s-2002-19835
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© Georg Thieme Verlag Stuttgart · New York

Depression and Panic Disorder after Heart Transplantation - Treatment with Sertraline

B.  Hesslinger1 , A.  Van de Loo2 , D.  Klecha1 , M.  Härter1 , S.  Schmidt-Schweda2
  • 1Department of Psychiatry and Psychotherapy, University of Freiburg, Germany
  • 2Department of Cardiology and Angiology, University of Freiburg, Germany
Further Information

Publication History

6. 11. 2000 · Revised 19. 3. 2001

12. 4. 2001

Publication Date:
30 January 2002 (online)

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This report focuses on a case of major depression and panic disorder after heart transplantation. Due to these disorders, the male patient’s compliance with cardiological treatment became increasingly insufficient. There are no controlled studies on psychopharmacological opportunities in cases such as this one. The patient was treated with sertraline and the outcome was healthy, without cardiovascular adverse effects or drug-drug interactions.

References

  • 1 Dew M A, Roth L H, Schulberg H C, Simmons R G, Kosmos R L, Trzepacz P T, Griffith B P. Prevalence and predictors of depression and anxiety-related disorders during the year after heart transplantation.  Gen Hosp Psychiatry. 1996;  18 (6Suppl) 48S-61S
    PubMedGoogle Scholar
  • 2 Glassman A H, Rodriguez A I, Shapiro P A. The Use of Antidepressant Drugs in Patients With Heart Disease.  J Clin Psychiatry. 1998;  59 (Suppl10) 16-21
    PubMedGoogle Scholar
  • 3 Maricle R A, Hosenpud J D, Normann D J, Woodbury A, Pantley G A, Cobanoglu A M, Starr A. Depression in patients being evaluated for heart transplantation.  Gen Hosp Psychiatry. 1989;  11 418-424
    PubMedGoogle Scholar
  • 4 Musselman D L, Evans D L, Nemeroff C B. The Relationship of Depression to Cardiovascular Disease. Epidemiology, Biology, and Treatment.  Arch Gen Psychiatry. 1998;  55 580-592
    PubMedGoogle Scholar
  • 5 Öström M, Eriksson A, Thorson J, Spigset O. Fatal overdose with citalopram.  Lancet. 1996;  348 339-340
    PubMedGoogle Scholar
  • 6 Pollack M H, Otto M W, Worthington J J, Manfro GG, Wolkow R. Sertraline in the Treatment of Panic Disorder. A Flexible-Dose Multicenter Trial.  Arch Gen Psychiatry. 1998;  55 1010-1016
    PubMedGoogle Scholar
  • 7 Shader R I, Greenblatt D J. Potassium, antipsychotic agents, arrythmias and sudden death.  J Clin Psychopharmacol. 1998;  18 427-428
    CrossrefPubMedGoogle Scholar
  • 8 Shapiro P A, Lesperance F, Frasure-Smith N, O'Conner C M, Baker B, Jiang J W, Dorian P, Harrison W, Glassman A H. An open-label preliminary trial of sertraline for treatment of major depression after acute myocardial infarction (the SADHAT Trial).  Am Heart J. 1999;  137 1100-1106
    PubMedGoogle Scholar

Dr. Bernd Hesslinger

Universitätsklinik für Psychiatrie und Psychosomatik
Abteilung für Psychiatrie und Psychotherapie

Hauptstr. 5

79104 Freiburg

Germany

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