Am J Perinatol 2001; 18(7): 393-396
DOI: 10.1055/s-2001-18698
ORIGINAL ARTICLES

Copyright © 2001 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4693

Transepidermal Water Loss and Skin Hydration in Preterm Infants During Phototherapy

A. Maayan-Metzger1 , G. Yosipovitch2 , E. Hadad2 , L. Sirota1
  • 1Department of Neonatology, Schneider Children's Medical Center of Israel, Petah Tiqva
  • 2Department of Dermatology, Rabin Medical Center, Beilinson Campus, Petah Tiqva, and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Further Information

Publication History

Publication Date:
03 December 2001 (online)

ABSTRACT

TEWL and skin hydration was measured in 7 body areas before and during phototherapy in 31 preterm infants (gestational age 25 to 36 weeks). Each patient served as his/her own control. There was a mean increase of 26.4% in TEWL during phototherapy. Most prominent increases were recorded in the cubital fossa (45.9%), groin (36.4%), and back (29%). There were no significant differences in stratum corneum moisture in six of the seven body areas before and during phototherapy. This study provides a better understanding of skin physiology during phototherapy in preterm infants and has important implications for the estimation of fluid replacement.

REFERENCES

  • 1 Cremer R J, Perryman P W, Richards D H. Influence of light on the hyperbilirubinemia of infants.  Lancet . 1958;  1 1097-1102
  • 2 Lucey J, Ferreiro M, Hewitt J. Prevention of hyperbilirubinemia of prematurity by phototherapy.  Pediatrics . 1968;  41 1047-1054
  • 3 Paul Y K, Wu M B, Hodgman J E. Insensible water loss in preterm infants: changes with postnatal development and non-ionizing radiant energy.  Pediatrics . 1974;  54 704-712
  • 4 Oh W, Karecki H. Phototherapy and insensible water loss in the newborn infant.  Am J Dis Child . 1972;  124 230-232
  • 5 Oh W, Yao A C, Hanson J S. The effects of phototherapy on peripheral blood flow and insensible water loss in newborn infants.  Clin Res . 1972;  20 283-287
  • 6 Kjartansson S, Hammarlund K, Sedin G. Insensible water loss from the skin during phototherapy in term and preterm infants.  Acta Pediatr . 1992;  81 764-768
  • 7 Harpin V A, Rutter N. Barrier properties of the newborn infant's skin.  J Pediatr . 1983;  102 419-425
  • 8 Evans N J, Rutter N K. Development of the epidermis in the newborn.  Biol Neonate . 1968;  47 74-80
  • 9 Nachman R L, Esterly N B. Increased skin permeability in preterm infants.  J Pediatr . 1971;  79 628-632
  • 10 Williams M L, Hanley K, Elias P M, Feingold K R. Ontogeny of the epidermal permeability barrier.  Investing Dermatol Symp Proc . 1998;  3 75-79
  • 11 Hammarlund K, Sedin G. Transepidermal water loss in newborn infants.  Acta Pediatr Scand . 1979;  68 795-801
  • 12 Rutter N, Hull D. Water loss from skin of term and preterm babies.  Arch Dis Child . 1979;  54 858-868
  • 13 Williams P R, Oh W. Effects of radiant warmer on insensible water loss in newborn infants.  Am J Dis Child . 1974;  128 511-514
  • 14 Lund C H, Nonato B L, Kuller J M, Franck L S, Cullander C, Durand D J. Disruption of barrier function in neonatal skin associated with adhesive removal.  J Pediatr . 1977;  131 367-372
  • 15 Washington J L, Bron A W, Starrett A L. The question of diarrhea and phototherapy.  Pediatrics . 1972;  49 279-280
  • 16 Yosipovitch G, Maayan-Metzger A, Merlob P, Sirota L. Skin barrier properties in different body areas in neonates.  Pediatrics . 2000;  106 105-108
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