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Endoscopy 2001; 33(3): 298
DOI: 10.1055/s-2001-12807
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© Georg Thieme Verlag Stuttgart · New York

Small Neuroendocrine Carcinoma of the Rectum Entirely Covered by an Adenomatous Component

H. Yoshikane, D. Arakawa, H. Kawashima, A. Sakakibara, H. Hidano, H. Takahashi, T. Yokoi
  • 1 Dept. of Internal Medicine, Handa City Hospital, Handa, Japan
  • 2 Dept. of Pathology, Handa City Hospital, Handa, Japan
  • 3 Division of Pathology, Aichi Medical University, Aichi, Japan
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Publication Date:
31 December 2001 (online)

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Figure 1 a Neuroendocrine carcinoma (NEC) of the large intestine is a rare condition with an extremely poor prognosis. At autopsy, a laterally spreading tumor (LST) 5 cm in diameter was found in the rectum in a 54-year-old woman who had multiple liver and bone metastases of unknown origin. b Cross section of the LST revealed, however, the coexistence of a whitish round tumor (arrow) beneath the brownish LST.

Figure 2Pathological examination revealed the LST to be a tubulovillous adenoma and the round tumor to be NEC. The extensive metastases resulted from the NEC which was just 1 cm in diameter (haematoxylin and eosin stain, original magnification × 12).

H. Yoshikane,M.D. 

Dept. of Internal Medicine
Handa City Hospital

2-29 Toyo, Handa
Aichi, 475
Japan

Fax: Fax:+ 81-569-243253

Email: E-mail:winwin@cac-net.ne.jp

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