SEVERE AORTIC THROMBOSIS IN THE NEONATE-SUCCESSFUL TREATMENT WITH LOW-MOLECULAR-WEIGHT HEPARIN: TWO CASE REPORTS AND REVIEW OF THE LITERATURE

Gil Klinger; Jonathan Hellmann; Alan Daneman

doi:10.1055/s-2000-9975

American Journal of Perinatology, Inhaltsverzeichnis

Am J Perinatol 2000; 17(3): 151-158
DOI: 10.1055/s-2000-9975

SEVERE AORTIC THROMBOSIS IN THE NEONATE-SUCCESSFUL TREATMENT WITH LOW-MOLECULAR-WEIGHT HEPARIN: TWO CASE REPORTS AND REVIEW OF THE LITERATURE

Gil Klinger^1,3 , Jonathan Hellmann^1,3 , Alan Daneman²³

¹Division of Neonatology, Department of Pediatrics, The Hospital for Sick Children, Toronto and the
²Department of Radiology, The Hospital for Sick Children, Toronto
³The University of Toronto, Toronto, Ontario, Canada

Abstract

ABSTRACT

Small- to moderate-sized aortic thrombi in the sick newborn are frequently demonstrated, however, severe aortic thrombosis is rarely encountered. We report two newborn infants presenting with signs of decreased lower limb perfusion shortly after birth. An occlusive infrarenal aortic thrombus was demonstrated in both infants by ultrasound. No predisposing condition for thrombosis could be found in the first infant; in the second, an umbilical arterial catheter was the likely cause. The infants were successfully treated with low-molecular-weight heparin. In both infants resolution of the thrombus was observed by ultrasound. No complications of treatment were encountered. The clinical spectrum of neonatal aortic thrombosis and treatment options are reviewed.

KEYWORD

Aortic thrombosis - neonate - low-molecular-weight heparin - treatment complications - review

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