Pharmacopsychiatry 1999; 32(6): 255-257
DOI: 10.1055/s-1999-7958
Case Report
Georg Thieme Verlag Stuttgart · New York

Gabapentin Leads to Remission of Somatoform Pain Disorder with Major Depression

I. Maurer, H. Volz, H. Sauer
  • Department of Psychiatry, Friedrich-Schiller-Universität Jena, Jena, Germany
Further Information

Publication History

Publication Date:
31 December 1999 (online)

Gabapentin, a novel antiepileptic drug, is effective in the treatment of partial seizures with and without secondary generalization. Evidence suggests that it may have mood-stabilizing and possibly antidepressant properties in bipolar depression. We report on a 48-year-old woman who had recurrent major depressive disorder. Following inguinal herniorrhaphy, she developed severe stabbing pain in the lower abdomen and inguinal area that progressed to constant pain in her whole body. She was depressive, hopeless, and had given up her social activities. A diagnosis of major depressive disorder and somatoform pain disorder was made. Antidepressants and carbamazepine were ineffective, and she had attempted suicide. Gabapentin resulted in remission of both the pain and the depressive mood at a dose of 1.800 mg/day.


MD I. Maurer,

Department of Psychiatry


Philosophenweg 3

D-07740 Jena


Email: [email protected]