Synlett 1991; 1991(10): 677-683
DOI: 10.1055/s-1991-21985
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Property-Directed Synthesis

George W. Gokel* , Julio C. Medina, Chensheng Li
  • *Department of Chemistry, University of Miami, Coral Gables, Florida 33124, USA
Further Information

Publication History

Publication Date:
13 March 2002 (online)

The ferrocene subunit has been used in the design and production of a family of small molecule receptors that have a molecular cleft which varies in size, shape, and electron richness. The criteria considered in their design and some aspects of their syntheses are discussed. 1. Introduction 2. A Family of Novel Structures Based upon Ferrocene 3. Small Molecule Complexing Systems 4. Ferrocene as a Small-Molecule Receptor Building Block 5. Selecting the Spacer Group 6. Synthetic Access 7. Binding Studies 8. Conclusions

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