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CC BY-NC-ND 4.0 · Journal of Fetal Medicine 2023; 10(04): 187-194
DOI: 10.1055/s-0044-1779752
SFM Practice Guidelines

SFM Fetal Therapy Practice Guidelines: Intrauterine Blood Transfusion

Seneesh Kumar Vikraman 
1   Centre for Prenatal Diagnosis and Fetal Therapy, ARMC AEGIS Hospital Perinthalmana and Aster MIMS hospital, Kottakal, Malappuram, Kerala, India
,
Manikandan Krishnan
2   Department of Fetal Medicine, The Fetal Clinic, Pondicherry, Kerala, India
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Abstract

Despite routine antenatal anti-D prophylaxis with immunoglobulin, Rh alloimmunization and hemolytic disease of the fetus and newborn continue to occur due to a myriad of reasons. Intrauterine intravascular transfusion (IUT) or fetal blood transfusion is a therapeutic prenatal procedure in which specifically prepared and treated unit of donor red blood cells is injected intravascularly into the umbilical vein under ultrasound guidance. Originally introduced in the year 1963, it continues to be the standard treatment for severe fetal anemia. The objective of this guideline is to provide an evidence-based update of IUT for the perinatal healthcare providers.

Keywords

ICT - intrauterine transfusion - MCA PSV - Rh D alloimmunization

Informed Consent

Informed consent was obtained from all women.




Publication History

Article published online:
21 March 2024

© 2024. Society of Fetal Medicine. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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