Abstract
The filamentous fungus Aspergillus causes a wide spectrum of diseases in the human lung, with Aspergillus fumigatus being the most pathogenic and allergenic subspecies. The broad range of clinical
syndromes that can develop from the presence of Aspergillus in the respiratory tract is determined by the interaction between host and pathogen.
In this review, an oversight of the different clinical entities of pulmonary aspergillosis
is given, categorized by their main pathophysiological mechanisms. The underlying
immune processes are discussed, and the main clinical, radiological, biochemical,
microbiological, and histopathological findings are summarized.
Keywords
Aspergillus
-
Aspergillus fumigatus
- immunology - pathophysiology
