Download PDF
Synfacts 2024; 20(01): 0089
DOI: 10.1055/s-0043-1763633
Innovative Drug Discovery and Development

ABBV-CLS-484, an Orally Bioavailable, Dual PTPN1/PTPN2 Phosphatase Inhibitor with Antitumor Activity

Authors

    Contributor(s):

  • Antonia F. Stepan (Roche)

  • Nicholas A. Meanwell (Baruch S. Blumberg Institute, U. Michigan)

Further Information
   Permissions and Reprints

Key words

phosphatase inhibitor - phosphate isostere - immunomodulatory - anti-tumor agent


Publication History

Article published online:
08 December 2023

© 2023. Thieme. All rights reserved

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany