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CC BY 4.0 · Journal of Child Science 2022; 12(01): e172-e181
DOI: 10.1055/s-0042-1757914
DOI: 10.1055/s-0042-1757914
Review Article
Measles-Associated CNS Complications: A Review
Authors
Abstract
Measles virus infection is a common infectious disease of childhood, incidence of which is still high in developing countries. Other than the morbidity associated with the acute systemic infection, the measles virus can cause serious fatal neural complications. It can either enter the brain leading to acute encephalitis like primary measles encephalitis and acute post infectious measles encephalomyelitis or it may persist in brain cells (as mutated virus) leading to long-term neurodegenerative diseases like measles inclusion body encephalitis and subacute sclerosing pan encephalitis. The patho-clinical features, treatment, and the outcomes of these complications are different and should be identified in time for early diagnosis and management.
Keywords
measles virus - primary measles encephalitis - acute post infectious measles encephalomyelitis - measles inclusion body encephalitis - subacute sclerosing pan encephalitisPublication History
Received: 02 July 2021
Accepted: 09 September 2022
Article published online:
06 November 2022
© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
Georg Thieme Verlag KG
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