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Semin Respir Crit Care Med 2022; 43(04): 536-540
DOI: 10.1055/s-0042-1748918
Review Article

Transbronchial Lung Cryobiopsy for Diffuse Parenchymal Lung Disease

Reza Ronaghi
1   Division of Pulmonary and Critical Care Medicine, Clinical Immunology and Allergy, David Geffen School of Medicine at UCLA, Los Angeles, California
,
Scott Oh
1   Division of Pulmonary and Critical Care Medicine, Clinical Immunology and Allergy, David Geffen School of Medicine at UCLA, Los Angeles, California
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Abstract

Transbronchial lung cryobiopsy (TBLC) offers a minimally invasive option for the diagnosis of diffuse parenchymal lung diseases, of which interstitial lung diseases comprise the most common diagnoses. It has a high diagnostic yield with prognostic and therapeutic implications. TBLC has a favorable safety profile compared with surgical lung biopsy, but associated complications include pneumothorax and bleeding. However, TBLC techniques remain variable. Here we review the latest techniques described to maximize diagnostic yield and mitigate complications of TBLC as well as how this modality has been incorporated into guidelines.

Keywords

transbronchial lung cryobiopsy - bronchoscopy - interstitial lung disease - diffuse parenchymal lung disease


Publication History

Article published online:
01 July 2022

© 2022. Thieme. All rights reserved.

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