Homeopathy 2023; 112(02): 120-124
DOI: 10.1055/s-0042-1748320
Original Research Article

Dynamized Aloysia Polystachya (Griseb.) Essential Oil: A Promising Antimicrobial Product

Talita Thomaz Nader
1   Department of Biotechnology, University of Ribeirão Preto (UNAERP), Ribeirão Preto, Sao Paulo, Brazil
Alexandre Henrique Leonel
2   Department of Research, Homeopatia Brasil, Franca, Sao Paulo, Brazil
Camila Yamasita Henrique
2   Department of Research, Homeopatia Brasil, Franca, Sao Paulo, Brazil
Silvia Helena Taleb Contini
1   Department of Biotechnology, University of Ribeirão Preto (UNAERP), Ribeirão Preto, Sao Paulo, Brazil
Eduardo José Crevelin
3   Department of Chemistry, Faculty of Philosophy, Sciences and Letters at Ribeirão Preto, University of São Paulo (USP), São Paulo, Sao Paulo, Brazil
Suzelei de Castro França
1   Department of Biotechnology, University of Ribeirão Preto (UNAERP), Ribeirão Preto, Sao Paulo, Brazil
Bianca Waléria Berton
1   Department of Biotechnology, University of Ribeirão Preto (UNAERP), Ribeirão Preto, Sao Paulo, Brazil
1   Department of Biotechnology, University of Ribeirão Preto (UNAERP), Ribeirão Preto, Sao Paulo, Brazil
› Author Affiliations
Funding None.


Background Compounds from vegetal matter have therapeutic potential to control highly prevalent microorganisms that are resistant to commonly used antimicrobial drugs. Dynamization of compounds can either maintain or improve their therapeutic effects, and make their use safer, especially those compounds whose therapeutic dose is close to the toxic limit. Aloysia polystachya (Griseb.) stands out among aromatic plants with antimicrobial potential.

Objective The aim of this study was to evaluate the antimicrobial activity of dynamized and crude forms of A. polystachya essential oil against Candida albicans, Escherichia coli and Staphylococcus aureus.

Methods Essential oil was extracted from A. polystachya dry leaves, solubilized, and dynamized at 1 cH potency as recommended by the Brazilian Homeopathic Pharmacopoeia. Antimicrobial activity against C. albicans, E. coli and S. aureus of the samples was assayed using the plate microdilution method.

Results Dynamized A. polystachya essential oil at the concentration of 1 μg/mL inhibited the growth of all the microbial species analyzed. The minimum inhibitory concentration of dynamized essential oil was smaller than crude essential oil for S. aureus, E. coli and C. albicans.

Conclusion It is reported for the first time that A. polystachya dynamized essential oil can effectively suppress microbial growth, and it is a promising adjuvant to treat infections with pathogenic S. aureus, E. coli and C. albicans.

Authors' Contributions

Talita T. Nader and Ana M.S. Pereira conceptualized the study. Eduardo J. Crevelin, Silvia H.T. Contini and Talita T. Nader contributed toward research methods. Bianca W. Bertoni, Alexandre H. Leonel and Camila Y. Henrique conducted the formal analysis and data investigation. Talita T. Nader and Ana M.S. Pereira wrote and prepared the original draft and completed the writing, review and editing of the final article. Ana M.S. Pereira and Suzelei C. França supervised the project.

Publication History

Received: 08 October 2021

Accepted: 27 January 2022

Article published online:
29 June 2022

© 2022. Faculty of Homeopathy. This article is published by Thieme.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

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