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DOI: 10.1055/s-0042-1743196
Emerging Multiple Parasite Reinfection as Neglected Tropical Disease: A Case Series
Funding None.
Abstract
Soil-transmitted helminth infection is endemic in Indonesia, with cases of reinfection despite individualized therapy and a mass treatment program. Three cases of multiple helminth infections were described that might be associated with chronic bloody diarrhea and stunted growth. These case series alert pediatricians that untreated helminthic infections are part of the differential diagnosis in children with gastrointestinal bleeding. Environmental surveillance should be performed in high-risk areas to prevent reinfection and growth alteration. In endemic areas, bloody diarrhea warns for an early routine fecal analysis. Correct diagnosis, prompt treatment, and source control are crucial to prevent long-term complications.
Consent for Publication
Written informed consent was obtained from the patient for the publication of this case report and accompanying images.
Authors' Contributions
F.S.A. coordinated the writing of the case series and was the attending senior consultant who examined the patient and performed a colonoscopy examination. A.A.P. helped in the drafting of the manuscript and follow-up of the patient, A.K. helped with parasitology examination of the patients and writing of discussion, and A.H.P. helped to draft the manuscript and supervise the project. All authors have read and approved the final version of the manuscript.
Publikationsverlauf
Eingereicht: 05. April 2021
Angenommen: 20. Dezember 2020
Artikel online veröffentlicht:
04. März 2022
© 2022. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
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References
- 1 Bethony J, Brooker S, Albonico M. et al. Soil-transmitted helminth infections: ascariasis, trichuriasis, and hookworm. Lancet 2006; 367 (9521): 1521-1532
- 2 Weatherhead JE, Hotez PJ, Mejia R. The global state of helminth control and elimination in children. Pediatr Clin North Am 2017; 64 (04) 867-877
- 3 Park MJ, Laksono B, Clements A, Sadler R, Stewart D. Worm-free children: an integrated approach to reduction of soil-transmitted helminth infections in Central Java. Rev Environ Health 2016; 31 (01) 111-113
- 4 Diniz-Santos DR, Jambeiro J, Mascarenhas RR, Silva LR. Massive Trichuris trichiura infection as a cause of chronic bloody diarrhea in a child. J Trop Pediatr 2006; 52 (01) 66-68
- 5 Zanwar VG, Pawar SV, Jain SS, Rathi SP, Contractor QQ, Rathi PM. An unusual cause of overt gastrointestinal bleeding in a malnourished child. Trop Doct 2016; 46 (02) 100-102
- 6 Tiwari K, Goyal S, Malvia S, Sanadhya A, Suman RL, Jain R. Impact on malnutrition on head size and development quotient. Int J Res Med Sci 2017; 24: 3003-3006
- 7 Zeehaida M, Zueter A, Zairi NZ, Zunulhisham S. Trichuris dysentery syndrome: do we learn enough from case studies?. Trop Biomed 2015; 32 (03) 545-550
- 8 Keiser J, Utzinger J. Efficacy of current drugs against soil-transmitted helminth infections: systematic review and meta-analysis. JAMA 2008; 299 (16) 1937-1948
- 9 Speich B, Ame SM, Ali SM. et al. Oxantel pamoate-albendazole for Trichuris trichiura infection. N Engl J Med 2014; 370 (07) 610-620
- 10 Mrus J, Baeten B, Engelen M, Silber SA. Efficacy of single-dose 500 mg mebendazole in soil-transmitted helminth infections: a review. J Helminthol 2018; 92 (03) 269-278
- 11 van der Werff SD, Vereecken K, van der Laan K. et al. Impact of periodic selective mebendazole treatment on soil-transmitted helminth infections in Cuban schoolchildren. Trop Med Int Health 2014; 19 (06) 706-718
- 12 Speich B, Moser W, Ali SM. et al. Efficacy and reinfection with soil-transmitted helminths 18-weeks post-treatment with albendazole-ivermectin, albendazole-mebendazole, albendazole-oxantel pamoate and mebendazole. Parasit Vectors 2016; 9: 123
- 13 Halpenny CM, Paller C, Koski KG, Valdés VE, Scott ME. Regional, household and individual factors that influence soil transmitted helminth reinfection dynamics in preschool children from rural indigenous Panamá. PLoS Negl Trop Dis 2013; 7 (02) e2070
- 14 Strunz EC, Addiss DG, Stocks ME, Ogden S, Utzinger J, Freeman MC. Water, sanitation, hygiene, and soil-transmitted helminth infection: a systematic review and meta-analysis. PLoS Med 2014; 11 (03) e1001620
- 15 Jia TW, Melville S, Utzinger J, King CH, Zhou XN. Soil-transmitted helminth reinfection after drug treatment: a systematic review and meta-analysis. PLoS Negl Trop Dis 2012; 6 (05) e1621