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Geburtshilfe Frauenheilkd 2016; 76(02): 156-163
DOI: 10.1055/s-0042-101168
Review
GebFra Science
Georg Thieme Verlag KG Stuttgart · New York

ABC3 Consensus Commented from the Perspective of the German Guidelines[*]

Third International Consensus Conference for Advanced Breast Cancer (ABC3), Lisbon, 07. 11. 2015ABC3-Konsensus vor dem Hintergrund deutscher Leitlinien kommentiertDritte Internationale Konsensuskonferenz zum fortgeschrittenen Mammakarzinom (ABC3), Lissabon, 07. 11. 2015
M. Untch
1   Klinik für Gynäkologie und Geburtshilfe, Interdisziplinäres Brustzentrum, HELIOS Klinikum Berlin-Buch, Berlin; Writing Committee
,
D. Augustin
2   Mammazentrum Ostbayern, DONAUISAR Klinikum Deggendorf, Deggendorf
,
J. Ettl
3   Frauenklinik und Poliklinik, Klinikum rechts der Isar, Technische Universität München, Munich
,
R. Haidinger
4   Brustkrebs Deutschland e. V. (patient representative)
,
N. Harbeck
5   Brustzentrum, Klinikum der Universität München, München; Writing Committee, ABC Panel Member
,
H.-J. Lück
6   Gynäkologisch-Onkologische Praxis, Hannover
,
D. Lüftner
7   Medizinische Klinik mit Schwerpunkt Hämatologie, Onkologie und Tumorimmunologie, Charité Berlin, Campus Benjamin Franklin, Berlin; Writing Committee
,
F. Marmé
8   Sektion Gynäkologische Onkologie, Nationales Centrum für Tumorerkrankungen (NCT), Heidelberg
,
L. Müller
9   Onkologie UnterEms, Leer-Emden-Papenburg
,
F. Overkamp
10   Medizinischer Onkologe, OncoConsult.Hamburg GmbH, Hamburg
,
E. Ruckhäberle
11   Frauenklinik, Universitätsklinikum Düsseldorf, Düsseldorf
,
M. Thill
12   Klinik für Gynäkologie und Geburtshilfe, Interdisziplinäres Brustzentrum, Agaplesion Markus Krankenhaus, Frankfurt am Main
,
C. Thomssen
13   Universitätsklinik und Poliklinik für Gynäkologie, Martin-Luther-Universität, Halle an der Saale; Writing Committee, ABC Panel Member
,
R. Wuerstlein
14   Brustzentrum, Klinikum der Universität München, Munich; Writing Committee
,
N. Marschner
15   Gemeinschaftspraxis für interdisziplinäre Onkologie und Hämatologie, Freiburg; Writing Committee
› Author Affiliations
Further Information

Publication History

received 29 December 2015
revised 29 December 2015

accepted 19 January 2016

Publication Date:
29 February 2016 (online)

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Abstract

The Third International Consensus Conference for Advanced Breast Cancer ABC3 on the diagnosis and treatment of advanced breast cancer was held in Lisbon from 5 to 7 November 2015. This year the focus was the treatment of metastatic breast cancer (stage IV) – including the patient perspectives. Important topics were questions relating to quality of life, the care for long-term survivors as well as the management of disease-related symptoms and treatment-based side effects. The use of standardised tools to assess individual treatment success and the benefits of new substances were important points for discussion. The diagnosis and treatment of inoperable locally advanced breast cancer were discussed two years ago during the ABC2 consensus [1]. A working group of German breast cancer experts commented on the results of the ABC panellists, paying particular attention to the German guidelines (AGO, S3, DGHO) on the diagnosis and treatment of breast cancer [2], [3], [4], [5] in Germany.

Zusammenfassung

Vom 05. bis 07. November 2015 fand in Lissabon die 3. internationale Konsensuskonferenz ABC3 (Advanced Breast Cancer Third Consensus) zu Diagnostik und Behandlung des fortgeschrittenen Mammakarzinoms statt. Der inhaltliche Schwerpunkt lag dieses Jahr auf der Behandlung des metastasierten Mammakarzinoms (Stadium IV) – u. a. unter besonderer Berücksichtigung der Perspektive der Patientinnen. Im Rahmen der Konsensusdiskussion wurde daher auch über Fragestellungen zur Lebensqualität, der Betreuung Langzeitüberlebender sowie des Umgangs mit erkrankungsbedingten Symptomen und therapiebedingten Nebenwirkungen abgestimmt. Neben den klassischen medizinischen Fragestellungen waren der Einsatz standardisierter Instrumente zur Bewertung des individuellen Therapieerfolgs sowie die Nutzenbewertung neuer Substanzen wichtige Diskussionspunkte. Diagnostik und Therapie des inoperablen lokal fortgeschrittenen Mammakarzinoms waren vor 2 Jahren anlässlich des ABC2-Konsensus diskutiert worden [1]. Eine Arbeitsgruppe deutscher Brustkrebsexperten hat die Abstimmungsergebnisse der ABC-Panelisten unter besonderer Berücksichtigung der deutschen Leitlinien (AGO, S3, DGHO) zu Diagnostik und Therapie des Mammakarzinoms [2], [3], [4], [5] für den Therapiealltag in Deutschland kommentiert.

Key words

ABC3 Consensus - Metastatic breast cancer - System therapy - Guidelines

Schlüsselwörter

ABC3-Konsensus - metastasiertes Mammakarzinom - Systemtherapie - Leitlinien

* The present manuscript (modified version) is a cross-section of opinions from the point of view of German breast cancer experts. The first publication was in “Breast Care” 01/2016 (Thomssen C, Augustin D, Ettl J et al., ABC3-Consensus: assessment by a German group of experts. DOI: 10.1159/000443515). The official ABC3 consensus will be published under the authorship of the ABC3 panelists.


Supporting Information

 

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