CC BY 4.0 · Aorta (Stamford) 2021; 09(06): 201-214
DOI: 10.1055/s-0041-1739466
State-of-the-Art Review

A New Era of Diagnosis and Therapy in Acute Aortic Syndromes: The Mainz–Essen Experience (Part II)—Management and Outcomes

Eduardo Bossone*
1   Division of Cardiology, Antonio Cardarelli Hospital, Naples, Italy
Riccardo Gorla*
2   Department of Cardiology, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy
Brigida Ranieri
3   Cardiovascular Imaging Division, IRCCS SDN (Scientific Institute for Research, Hospitalization and Healthcare), Naples, Italy
Valentina Russo
4   Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy
Heinz Jakob
5   Department of Thoracic and Cardiovascular Surgery, West German Heart Center, University of Duisburg-Essen, University Hospital Essen, Essen, Germany
Raimund Erbel
6   Institute for Medical Informatics, Biometry and Epidemiology (IMIBE), University of Duisburg-Essen, University Hospital Essen, Essen, Germany
› Author Affiliations
Funding None.


Over the years, the cardiovascular department of Johannes Gutenberg University in Mainz-West-German Heart Centre in Essen (Germany) designed and implemented the hybrid operating room (2003) along with advanced endovascular and surgical procedures, including the frozen elephant trunk technique. For the study purpose, the Mainz–Essen experience on acute aortic syndromes was summarized by considering original articles from single-center or multicenter studies performed at West German Heart Centre, Essen, Germany, or at the cardiovascular department of Johannes Gutenberg University, Mainz, Germany. We present the 35-year-long Mainz–Essen research, education, and patient management journey in creating an integrated multidisciplinary “Aortic Center” in the heart of Europe.

* These authors contributed equally to this work.

Supplementary Material

Publication History

Received: 05 June 2020

Accepted: 02 July 2021

Article published online:
28 December 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (

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