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Semin intervent Radiol 2021; 38(04): 412-418
DOI: 10.1055/s-0041-1733903
Review Article

Lobar Radioembolization for Intermediate and Advanced Hepatocellular Carcinoma: Retrospective and Prospective Data

Janesh Lakhoo
1   Department of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee
,
Thomas H. Perez
1   Department of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee
,
Anthony J. Borgmann
1   Department of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee
,
Daniel B. Brown
1   Department of Radiology, Vanderbilt University Medical Center, Nashville, Tennessee
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Abstract

Historically, outcomes reporting for radioembolization with yttrium-90 (90Y) of hepatocellular carcinoma has included patients across the range of Barcelona Clinic Liver Cancer (BCLC) stages. With the potential for curative radiation segmentectomy for BCLC 0/A patients and evolution of systemic therapy for BCLC C patients, focused review by group is of increasing interest. In this review, we report on efficacy of 90Y in patients with intermediate (BCLC B) and advanced (BCLC C) hepatocellular carcinoma as well as expected toxicities. Additionally, we review existing trials comparing 90Y to transarterial chemoembolization and systemic treatments in these patient groups and outline future studies.

Keywords

hepatocellular carcinoma - Barcelona Clinic Liver Cancer - radioembolization - chemoembolization - interventional radiology


Publikationsverlauf

Artikel online veröffentlicht:
07. Oktober 2021

© 2021. Thieme. All rights reserved.

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