Subscribe to RSS
Download PDF
DOI: 10.1055/s-0041-1733874
Childhood Immunoglobulin A Vasculitis Associated with COVID-19: A Case Report
Authors
Funding None.
Abstract
Primary immunoglobulin A vasculitis (IgAV) is one the most common childhood vasculitis. A 5-year and 10-month-old girl child patient presented with confluent palpable purple red rash, mainly over both ankles. This was associated with edematous, tender ankles, limited range of movement, and inability to walk. A concomitant coronavirus disease 2019 (COVID-19) was documented by nasopharyngeal swab. This case suggested that COVID-19 can trigger IgAV in children. Hence, awareness of COVID-19 infection in IgAV should be present, and it may be useful to investigate COVID-19 as one of the causes of IgAV, especially in the presence of an epidemic.
Publication History
Received: 07 April 2021
Accepted: 14 June 2021
Article published online:
11 August 2021
© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany
-
References
- 1 Piram M, Maldini C, Biscardi S. et al. Incidence of IgA vasculitis in children estimated by four-source capture-recapture analysis: a population-based study. Rheumatology (Oxford) 2017; 56 (08) 1358-1366
- 2 Oni L, Sampath S. Childhood IgA vasculitis (Henoch Schonlein purpura)-advances and knowledge gaps. Front Pediatr 2019; 7: 257-257
- 3 Gardner-Medwin JM, Dolezalova P, Cummins C, Southwood TR. Incidence of Henoch-Schönlein purpura, Kawasaki disease, and rare vasculitides in children of different ethnic origins. Lancet 2002; 360 (9341): 1197-1202
- 4 Wang JJ, Xu Y, Liu FF. et al. Association of the infectious triggers with childhood Henoch-Schonlein purpura in Anhui province, China. J Infect Public Health 2020; 13 (01) 110-117
- 5 Hwang HH, Lim IS, Choi B-S, Yi DY. Analysis of seasonal tendencies in pediatric Henoch-Schönlein purpura and comparison with outbreak of infectious diseases. Medicine (Baltimore) 2018; 97 (36) e12217-e12217
- 6 Mazumder S, Ma M, Champigny M, Adeyemo A. A case of adult-onset Henoch-Schönlein purpura triggered by fire ants. Cureus 2020; 12 (03) e7341-e7341
- 7 Shao WX, Ye Q, Wang XJ. Application value of laboratory indexes in the differential diagnosis of Henoch-Schoenlein purpura. Z Rheumatol 2017; 76 (04) 351-356
- 8 Allez M, Denis B, Bouaziz JD. et al. COVID-19-related IgA vasculitis. Arthritis Rheumatol 2020; 72 (11) 1952-1953
- 9 Iba T, Connors JM, Levy JH. The coagulopathy, endotheliopathy, and vasculitis of COVID-19. Inflamm Res 2020; 69 (12) 1181-1189
- 10 Castelnovo L, Capelli F, Tamburello A, Faggioli PM, Mazzone A. Symmetric cutaneous vasculitis in COVID-19 pneumonia. J Eur Acad Dermatol Venereol 2020; 34 (08) e362-e363
- 11 Ozen S, Pistorio A, Iusan SM. et al; Paediatric Rheumatology International Trials Organisation (PRINTO). EULAR/PRINTO/PRES criteria for Henoch-Schönlein purpura, childhood polyarteritis nodosa, childhood Wegener granulomatosis and childhood Takayasu arteritis: Ankara 2008. Part II: final classification criteria. Ann Rheum Dis 2010; 69 (05) 798-806
- 12 Varga Z, Flammer AJ, Steiger P. et al. Endothelial cell infection and endotheliitis in COVID-19. Lancet 2020; 395 (10234): 1417-1418
- 13 Schett G, Manger B, Simon D, Caporali R. COVID-19 revisiting inflammatory pathways of arthritis. Nat Rev Rheumatol 2020; 16 (08) 465-470