CC BY-NC-ND 4.0 · Ann Natl Acad Med Sci
DOI: 10.1055/s-0041-1731597
Review Article

A Step Toward Optimizing Regenerative Medicine Principle to Combat COVID-19

1  Department of Paediatric Surgery, All India Institute of Medical Sciences, New Delhi, India
2  Department of Orthopaedics, School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India
3  Department of Orthopaedics, Government Medical College and Hospital, Dindigul, Tamil Nadu, India
4  Department of Plastic Surgery, Topiwala National Medical College and BYL Nair Ch. Hospital, Mumbai, Maharashtra, India
5  Department of Orthopaedics, Kasturba Medical College, MAHE University, Manipal, Karnataka, India
6  Department of Orthopedics, Sri Devaraj URS Medical College, Kolar, Karnataka, India
7  Biocon Biologics, Chennai, Tamil Nadu, India
8  Department of Microbiology, PSG BioNEST, PSG TECH, Coimbatore, Tamil Nadu, India
9  School of Medical Sciences and Research, Sharda University, Greater Noida, Uttar Pradesh, India
10  Department of Biotechnology, School of Engineering and Technology, Sharda University, Greater Noida, Uttar Pradesh, India
› Author Affiliations


Drugs are currently not licensed in specific to pulverize COVID-19. On an emergency basis, vaccines were approved to prevent the further spread of COVID-19. This serves as a potential background for considering the optimization of biologics. In this context, evidence on convalescent plasma and stem cells has shown a beneficial role. Here, we have considered this as plausible therapy, and further hypothesize that their cocktails will synergistically boost the immunogenicity to relegate COVID-19. This warrants a large volume clinical trial on an emergent basis, because the sooner we establish a safe and effective cure, the better.

Publication History

Publication Date:
21 June 2021 (online)

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