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J Am Acad Audiol 2021; 32(05): 308-314
DOI: 10.1055/s-0041-1728718
Research Article

Tone Burst Masseter Vestibular Evoked Myogenic Potentials: Normative Values and Test–Retest Reliability

Sangu Srinivasan Vignesh
1   Department of Neurology, Tamil Nadu Government Multi Super Speciality Hospital, Chennai, Tamil Nadu, India
,
Niraj Kumar Singh
2   Department of Audiology, All India Institute of Speech and Hearing, Mysuru, Karnataka, India
,
Krishna Rajalakshmi
2   Department of Audiology, All India Institute of Speech and Hearing, Mysuru, Karnataka, India
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Abstract

Background Masseter vestibular evoked myogenic potential (mVEMP) is a recent tool for the assessment of vestibular and trigeminal pathways. Though a few studies have recorded mVEMP using click stimuli, there are no reports of these potentials using the more conventional VEMP eliciting stimuli, the tone bursts.

Purpose The aim of the study is to establish normative values and determine the test–retest reliability of tone burst evoked mVEMP.

Research Design The research design type is normative study design.

Study Sample Forty-four healthy participants without hearing and vestibular deficits in the age range of 18 to 50 years participated in the study.

Data Collection and Analysis All participants underwent mVEMP testing using 500 Hz tone-burst stimuli at 125 dB peSPL. Ten participants underwent second mVEMP testing within 1 month of the initial testing to estimate the test–retest reliability.

Results Tone burst mVEMP showed robust responses in all participants. There were no significant ear and sex differences on any mVEMP parameter (p > 0.05); however, males had significantly higher EMG normalized peak-to-peak amplitude than females. Intraclass correlation coefficient (ICC) values of tone burst mVEMP showed excellent test–retest reliability (ICC >0.75) for ipsilateral and contralateral p11 latency, ipsilateral EMG normalized p11-n21 peak to peak amplitude, and amplitude asymmetry ratio. Fair and good test–retest reliability (0.4 < ICC > 0.75) was observed for ipsilateral and contralateral n21 latency, contralateral EMG normalized peak-to-peak amplitude, and amplitude asymmetry ratio.

Conclusion Tone burst mVEMP is a robust and reliable test for evaluating the functional integrity of the vestibulomasseteric reflex pathway.

Keywords

vestibulomasseteric reflex - evoked potentials - otolith responses - trigeminal nerve


Publication History

Received: 18 September 2020

Accepted: 30 November 2020

Article published online:
01 June 2021

© 2021. American Academy of Audiology. This article is published by Thieme.

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 

  • References

  • 1 Rosengren SM, Colebatch JG, Young AS, Govender S, Welgampola MS. Vestibular evoked myogenic potentials in practice: methods, pitfalls and clinical applications. Clin Neurophysiol Pract 2019; 4: 47-68
    CrossrefPubMedSearch in Google Scholar
  • 2 Rudisill HE, Hain TC. Lower extremity myogenic potentials evoked by acoustic stimuli in healthy adults. Otol Neurotol 2008; 29 (05) 688-692
    CrossrefPubMedSearch in Google Scholar
  • 3 Cherchi M, Bellinaso NP, Card K. et al. Sound evoked triceps myogenic potentials. Otol Neurotol 2009; 30 (04) 545-550
    CrossrefPubMedSearch in Google Scholar
  • 4 Ferber-Viart C, Soulier N, Dubreuil C, Duclaux R. Cochleovestibular afferent pathways of trapezius muscle responses to clicks in human. Acta Otolaryngol 1998; 118 (01) 6-10
    CrossrefPubMedSearch in Google Scholar
  • 5 Deriu F, Tolu E, Rothwell JC. A sound-evoked vestibulomasseteric reflex in healthy humans. J Neurophysiol 2005; 93 (05) 2739-2751
    CrossrefPubMedSearch in Google Scholar
  • 6 de Natale ER, Ginatempo F, Paulus KS. et al. Paired neurophysiological and clinical study of the brainstem at different stages of Parkinson's disease. Clin Neurophysiol 2015; 126 (10) 1871-1878
    CrossrefPubMedSearch in Google Scholar
  • 7 Deriu F, Tolu E, Rothwell JC. A short latency vestibulomasseteric reflex evoked by electrical stimulation over the mastoid in healthy humans. J Physiol 2003; 553 (Pt 1): 267-279
    CrossrefPubMedSearch in Google Scholar
  • 8 Deriu F, Ortu E, Capobianco S. et al. Origin of sound-evoked EMG responses in human masseter muscles. J Physiol 2007; 580 (Pt 1): 195-209
    CrossrefPubMedSearch in Google Scholar
  • 9 Deriu F, Giaconi E, Rothwell JC, Tolu E. Reflex responses of masseter muscles to sound. Clin Neurophysiol 2010; 121 (10) 1690-1699
    CrossrefPubMedSearch in Google Scholar
  • 10 Magnano I, Pes GM, Pilurzi G. et al. Exploring brainstem function in multiple sclerosis by combining brainstem reflexes, evoked potentials, clinical and MRI investigations. Clin Neurophysiol 2014; 125 (11) 2286-2296
    CrossrefPubMedSearch in Google Scholar
  • 11 Magnano I, Pes GM, Cabboi MP. et al. Comparison of brainstem reflex recordings and evoked potentials with clinical and MRI data to assess brainstem dysfunction in multiple sclerosis: a short-term follow-up. Neurol Sci 2016; 37 (09) 1457-1465
    CrossrefPubMedSearch in Google Scholar
  • 12 de Natale ER, Ginatempo F, Paulus KS. et al. Abnormalities of vestibular-evoked myogenic potentials in idiopathic Parkinson's disease are associated with clinical evidence of brainstem involvement. Neurol Sci 2015; 36 (06) 995-1001
    CrossrefPubMedSearch in Google Scholar
  • 13 De Natale ER, Ginatempo F, Mercante B. et al. Vestibulo masseteric reflex and acoustic masseteric Reflex. Normative data and effects of age and gender. Clin Neurophysiol 2019; 130 (09) 1511-1519
    CrossrefPubMedSearch in Google Scholar
  • 14 Ginatempo F, Ortu E, Pilurzi G, Tolu E, Deriu F. Vestibulo-masseteric reflex (VMR) and acoustic-masseteric reflex (AMR): normative values. Clin Neurophysiol 2013; 124: 216
    CrossrefSearch in Google Scholar
  • 15 Akin FW, Murnane OD, Proffitt TM. The effects of click and tone-burst stimulus parameters on the vestibular evoked myogenic potential (VEMP). J Am Acad Audiol 2003; 14 (09) 500-509 , quiz 534–535
    Thieme ConnectPubMedSearch in Google Scholar
  • 16 Deepak DT, Bhat JS, Kumar K. Ocular vestibular evoked myogenic potential using different test stimuli. ISRN Otolaryngol 2013; 2013: 161937
    CrossrefPubMedSearch in Google Scholar
  • 17 Murnane OD, Akin FW, Kelly KJ, Byrd S. Effects of stimulus and recording parameters on the air conduction ocular vestibular evoked myogenic potential. J Am Acad Audiol 2011; 22 (07) 469-480
    Thieme ConnectPubMedSearch in Google Scholar
  • 18 Welgampola MS, Colebatch JG. Characteristics of tone burst-evoked myogenic potentials in the sternocleidomastoid muscles. Otol Neurotol 2001; 22 (06) 796-802
    CrossrefPubMedSearch in Google Scholar
  • 19 Park HJ, Lee I-S, Shin JE, Lee YJ, Park MS. Frequency-tuning characteristics of cervical and ocular vestibular evoked myogenic potentials induced by air-conducted tone bursts. Clin Neurophysiol 2010; 121 (01) 85-89
    CrossrefPubMedSearch in Google Scholar
  • 20 Singh NK, Keloth NK, Sinha S. Is there a safe level for recording vestibular evoked myogenic potential? Evidence from cochlear and hearing function tests. Ear Hear 2019; 40 (03) 493-500
    CrossrefPubMedSearch in Google Scholar
  • 21 Welgampola MS, Colebatch JG. Vestibulocollic reflexes: normal values and the effect of age. Clin Neurophysiol 2001; 112 (11) 1971-1979
    CrossrefPubMedSearch in Google Scholar
  • 22 Versino M, Colnaghi S, Callieco R, Cosi V. Vestibular evoked myogenic potentials: test-retest reliability. Funct Neurol 2001; 16 (04) 299-309
    PubMedSearch in Google Scholar
  • 23 Kumar K, Sinha SK, Bharti AK, Barman A. Comparison of vestibular evoked myogenic potentials elicited by click and short duration tone burst stimuli. J Laryngol Otol 2011; 125 (04) 343-347
    CrossrefPubMedSearch in Google Scholar
  • 24 Özgür A, Çelebi Erdivanlı Ö, Özergin Coşkun Z. et al. Comparison of tone burst, click and chirp stimulation in vestibular evoked myogenic potential testing in healthy people. J Int Adv Otol 2015; 11 (01) 33-35
    CrossrefPubMedSearch in Google Scholar
  • 25 Wu H-J, Shiao A-S, Yang Y-L, Lee G-S. Comparison of short tone burst-evoked and click-evoked vestibular myogenic potentials in healthy individuals. J Chin Med Assoc 2007; 70 (04) 159-163
    CrossrefPubMedSearch in Google Scholar
  • 26 Ochi K, Ohashi T. Age-related changes in the vestibular-evoked myogenic potentials. Otolaryngol Head Neck Surg 2003; 129 (06) 655-659
    CrossrefPubMedSearch in Google Scholar
  • 27 Sung P-H, Cheng P-W, Young Y-H. Effect of gender on ocular vestibular-evoked myogenic potentials via various stimulation modes. Clin Neurophysiol 2011; 122 (01) 183-187
    CrossrefPubMedSearch in Google Scholar
  • 28 Miller JD. Sex differences in the length of the organ of Corti in humans. J Acoust Soc Am 2007; 121 (04) EL151-EL155
    CrossrefPubMedSearch in Google Scholar
  • 29 Raadsheer MC, Kiliaridis S, Van Eijden TMGJ, Van Ginkel FC, Prahl-Andersen B. Masseter muscle thickness in growing individuals and its relation to facial morphology. Arch Oral Biol 1996; 41 (04) 323-332
    CrossrefPubMedSearch in Google Scholar
  • 30 Kress B, Schindler M, Rasche D. Why do advanced age and female gender predispose to trigeminal neuralgia?. Clin Neuroradiol 2008; 18: 60-64
    CrossrefSearch in Google Scholar
  • 31 McCaslin DL, Fowler A, Jacobson GP. Amplitude normalization reduces cervical vestibular evoked myogenic potential (cVEMP) amplitude asymmetries in normal subjects: proof of concept. J Am Acad Audiol 2014; 25 (03) 268-277
    Thieme ConnectPubMedSearch in Google Scholar
  • 32 Xie S-J, Xu Y, Bi H-Z, Jia H-B, Zheng Y-J, Zhang Y-G. Ocular vestibular-evoked myogenic potentials in healthy pilots and student pilots. Aviat Space Environ Med 2011; 82 (07) 729-733
    CrossrefPubMedSearch in Google Scholar