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CC BY-NC-ND 4.0 · Thorac Cardiovasc Surg Rep 2021; 10(01): e18-e21
DOI: 10.1055/s-0040-1722705
Case Report: Cardiac

Acute Type A Dissection during Pregnancy with Marfan's Syndrome

Christian Heim 
1   Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany
,
Philipp P. Müller
1   Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany
,
Michael Weyand
1   Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany
,
Frank Harig
1   Department of Cardiac Surgery, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany
› Author Affiliations Funding This publication was supported by Deutsche Forschungsgemeinschaft and University of Erlangen Foundation within the funding programme Open Access Publishing.
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Abstract

Background Marfan's syndrome (MFS) is a connective tissue disorder, caused by a mutation in the FBN-1 gene and affecting multiple organ systems including the vascular system. During pregnancy, women with MFS have an increased risk of aortic dissection due to changes in the cardiovascular system.

Case Description We present a 39-year-old woman that suffered from an acute aortic dissection in week 33 of her third pregnancy who urgently required lifesaving surgery. Three-dimensional reconstruction of computed tomography scan was performed with unborn child in utero.

Conclusion Monitoring of patients with suspected or confirmed MFS appears essential and interdisciplinary treatment and prevention strategies are required.

Keywords

aortic dissection - Marfan - pregnancy

Authors' Contribution

Concept/design and critical revision of article were done by C.H. and M.W. Also, C.H. contributed in funding. Data interpretation and drafting article were done by F.H. and P.P.M., respectively.


Institutional Review Board Waiver and Patient Consent Statement

Patient signed informed consent related to clinical course, therefore and due to its retrospective nature of the educational case report, the Institutional Review Board was waived.




Publication History

Received: 05 November 2020

Accepted: 24 November 2020

Article published online:
11 March 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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