CC BY-NC-ND 4.0 · International Journal of Practical Otolaryngology 2021; 04(01): e1-e5
DOI: 10.1055/s-0040-1722335
Case Report

A Case of Sudden Diffuse Thyroid Swelling after Fine Needle Aspiration Cytology where Changes over Time Were Confirmed by Ultrasonography

Naoki Takemoto
1   Department of Otolaryngology, Head and Neck Surgery, Nagoya City University, Nagoya, Japan
2   Department of Otolaryngology, Toyohashi Municipal Hospital, Toyohashi, Japan
,
Taijiro Ozawa
2   Department of Otolaryngology, Toyohashi Municipal Hospital, Toyohashi, Japan
,
Hitomi Tamai
2   Department of Otolaryngology, Toyohashi Municipal Hospital, Toyohashi, Japan
,
Tatsuhiro Asaoka
2   Department of Otolaryngology, Toyohashi Municipal Hospital, Toyohashi, Japan
,
Shinichi Iwasaki
1   Department of Otolaryngology, Head and Neck Surgery, Nagoya City University, Nagoya, Japan
› Author Affiliations

Abstract

We encountered a case of diffuse thyroid swelling after fine needle aspiration (dTSaFNA) cytology, and monitored the swelling by thyroid ultrasonography. The scan findings are reported. A 57-year-old female visited our hospital complaining of swelling in her anterior neck. She had a history of metal allergy and was not taking any medications. Because a solid cystic tumor was detected in the left thyroid lobe, we decided to perform fine-needle aspiration cytology (FNAC). When the second aspiration was performed with a 22G needle inserted into the nodule in the left lobe, the patient immediately complained of pain in her neck. Within 2 minutes, her anterior neck swelled up and ultrasonography showed vascular dilatation in the left thyroid lobe. Neck cooling with steroid injection was undertaken. However, over the next 5 minutes, the vascular dilatation also spread to the right lobe. About 15 minutes later, the vessels gradually became unclear, and the neck pain and swelling persisted, and the patient was hospitalized for observation. By the following day, all the symptoms and signs had resolved and the patient was discharged. FNA is associated with the risk of neck swelling caused by hemorrhage or dTSaFNA. To make a prompt diagnosis and provide appropriate treatment for this complication, ultrasonography could be useful.



Publication History

Received: 11 May 2020

Accepted: 13 August 2020

Article published online:
07 January 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • References

  • 1 Sumiyoshi S, Murakami M, Noguchi H. et al. Hematoma formation and thyroid diffuse swelling after thyroid fine needle aspiration cytology. Endocr J 2011; 87: 41-43
  • 2 Van den Bruel A, Roelandt P, Drijkoningen M, Hudders JP, Decallonne B, Bouillon R. A thyroid thriller: acute transient and symmetric goiter after fine-needle aspiration of a solitary thyroid nodule. Thyroid 2008; 18 (01) 81-84
  • 3 Ohtsuka Y, Nemoto T, Kunii N, Hanazawa T, Okamoto Y. Three cases of neck swelling after FNAC (fine-needle aspiration cytology). Nippon Jibiinkoka Gakkai Kaiho 2016; 119 (09) 1225-1230
  • 4 Thyroid Terminology and Diagnostic Criteria Committee. Japan Association of Breast and Thyroid Sonology: Thyroid Ultrasound – A Guidebook for Diagnosis and Management. 3rd revised ed.. Tokyo: Nankodo; 2016: 50
  • 5 Polyzos SA, Anastasilakis AD. Systematic review of cases reporting blood extravasation-related complications after thyroid fine-needle biopsy. J Otolaryngol Head Neck Surg 2010; 39 (05) 532-541
  • 6 Nakagawa Y, Mori K, Hirabayashi S. et al. A case of sudden diffuse thyroid swelling after fine needle aspiration cytology. Endocr J 2007; 88: 348
  • 7 Tsuzuki N, Kawasaki T, Sahara S. et al. A case of giant goiter with sudden neck swelling after fine needle aspiration cytology, and requiring intubation. Journal of the Japan Broncho-Esophagological Society 2019; 70: S79
  • 8 Roh JL. Intrathyroid hemorrhage and acute upper airway obstruction after fine needle aspiration of the thyroid gland. Laryngoscope 2006; 116 (01) 154-156
  • 9 Noordzij JP, Goto MM. Airway compromise caused by hematoma after thyroid fine-needle aspiration. Am J Otolaryngol 2005; 26 (06) 398-399
  • 10 Park MH, Yoon JH. Anterior neck hematoma causing airway compression following fine needle aspiration cytology of the thyroid nodule: a case report. Acta Cytol 2009; 53 (01) 86-88
  • 11 Chikano S, Kurokawa M, Yamada S. et al. Two cases of sudden diffuse thyroid swelling after fine needle aspiration cytology. Journal of the Japan Otorhinolaryngologists Society 2015; 108: 783-790
  • 12 Gharib H, Papini E, Paschke R. et al; AACE/AME/ETA Task Force on Thyroid Nodules. American Association of Clinical Endocrinologists, Associazione Medici Endocrinologi, and European Thyroid Association Medical guidelines for clinical practice for the diagnosis and management of thyroid nodules: executive summary of recommendations. Endocr Pract 2010; 16 (03) 468-475
  • 13 Layfield LJ, Cibas ES, Gharib H, Mandel SJ. Thyroid aspiration cytology: current status. CA Cancer J Clin 2009; 59 (02) 99-110
  • 14 Degirmenci B, Haktanir A, Albayrak R. et al. Sonographically guided fine-needle biopsy of thyroid nodules: the effects of nodule characteristics, sampling technique, and needle size on the adequacy of cytological material. Clin Radiol 2007; 62 (08) 798-803
  • 15 Yanase Y, Hirokawa M, Maekawa M. et al. Quality control of sample collection and smear method in thyroid fine needle aspiration cytology. J Jpn Soc Clin Cytol 2010; 49: 431-436
  • 16 Yamada H, Koshikawa T, Suganuma Y. et al. Ultrasound-guided fine needle non-aspiration cytology at thyroid and neck lymph node. J Jpn Soc Clin Cytol 2006; 45: 84-90