CC BY 4.0 · Journal of Child Science 2020; 10(01): e212-e214
DOI: 10.1055/s-0040-1721142
Case Report

Negative Pressure Pulmonary Edema as a Cause of Diffuse Alveolar Hemorrhage in the Newborn

Alejandro Donoso
1  Pediatric Intensive Care Unit, Hospital Clínico Metropolitano La Florida, Santiago, Chile
,
Gianfranco Tomarelli
1  Pediatric Intensive Care Unit, Hospital Clínico Metropolitano La Florida, Santiago, Chile
,
Daniela Arriagada
1  Pediatric Intensive Care Unit, Hospital Clínico Metropolitano La Florida, Santiago, Chile
› Author Affiliations

Abstract

Negative pressure pulmonary edema (NPPE) is a rare entity that can become life threatening. Its development in neonates is very rare, and its presentation as alveolar hemorrhage is uncommon. We report a case of a newborn 23 days old, previously healthy, who presented an episode of choking during breastfeeding. This progressed to acute respiratory failure due to diffuse alveolar hemorrhage. A few hours after admission, the newborn developed refractory hypoxemia, requiring high-frequency oscillatory ventilation and nitric oxide therapy for 24 hours. NPPE was postulated as a diagnosis of exclusion. The newborn recovered completely. NPPE should always be considered in a case with recent obstruction of the upper airway, even in unusual age groups. Sometimes it can manifest as alveolar hemorrhage.



Publication History

Received: 03 August 2020

Accepted: 14 October 2020

Publication Date:
02 December 2020 (online)

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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