CC BY 4.0 · Journal of Child Science 2020; 10(01): e141-e147
DOI: 10.1055/s-0040-1717140
Original Article

Clinical Profile of Episodic Wheezing and Multiple Trigger Wheezing in Preschool Children: A Cross-Sectional Study

Lalsiama Tualzik
1  Department of Pediatrics, District Hospital Mamit, Mizoram, India
2  Department of Pediatrics, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India
› Author Affiliations


The objectives of our study were to identify the relative frequency of episodic viral wheeze (EVW) and multiple trigger wheeze (MTW) in preschool children of 1 to 5 years of age with recurrent wheezing and to compare the relevant clinical and sociodemographic parameters in the above phenotypes. This cross-sectional study included 165 children aged 1 to 5 years with recurrent wheeze. Participants were categorized into EVW and MTW based on history according to European Respiratory Society Task Force recommendations 2008. Symptom control was assessed by Global Initiative for Asthma guidelines 2015. Of the total participants, EVW was seen in 55% and MTW in 45%. Children with MTW were significantly older than those with EVW, more atopic, and had higher eosinophil counts. The dominant phenotype seen in our study was EVW. The absence of ocular/nasal allergy and exclusive breastfeeding predicted well-controlled symptoms in EVW and in all preschool wheezers, respectively.

Authors' Contributions

Both the authors were involved in the study design, data collection, analysis, literature review, and drafting of the manuscript, and reviewed the manuscript for intellectual content and seen and approved the final draft. The authors agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

Publication History

Received: 26 July 2020

Accepted: 20 August 2020

Publication Date:
15 October 2020 (online)

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (

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