Am J Perinatol 2020; 37(10): 1022-1030
DOI: 10.1055/s-0040-1713416
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

The Impact of COVID-19 Infection on Labor and Delivery, Newborn Nursery, and Neonatal Intensive Care Unit: Prospective Observational Data from a Single Hospital System

1  Department of Pediatrics, Morristown Medical Center, Morristown, New Jersey
2  Department of Clinical and Transnational Research, Biomedical Research Institute of New Jersey, Cedar Knolls, New Jersey
3  MidAtlantic Neonatal Associates, Morristown, New Jersey
,
Farah Benarba
4  Department of Obstetrics and Gynecology, Morristown Medical Center, Morristown, New Jersey
,
Caryn Peters
1  Department of Pediatrics, Morristown Medical Center, Morristown, New Jersey
3  MidAtlantic Neonatal Associates, Morristown, New Jersey
,
Yinka Oyelese
5  Department of Maternal Fetal Medicine, Morristown Medical Center, Morristown, New Jersey
,
Tom Murphy
1  Department of Pediatrics, Morristown Medical Center, Morristown, New Jersey
3  MidAtlantic Neonatal Associates, Morristown, New Jersey
,
Diana Contreras
4  Department of Obstetrics and Gynecology, Morristown Medical Center, Morristown, New Jersey
,
Christina Gagliardo
1  Department of Pediatrics, Morristown Medical Center, Morristown, New Jersey
,
Eberechi Nwaobasi-Iwuh
1  Department of Pediatrics, Morristown Medical Center, Morristown, New Jersey
,
M. Cecilia DiPentima
1  Department of Pediatrics, Morristown Medical Center, Morristown, New Jersey
,
Andrew Schenkman
1  Department of Pediatrics, Morristown Medical Center, Morristown, New Jersey
2  Department of Clinical and Transnational Research, Biomedical Research Institute of New Jersey, Cedar Knolls, New Jersey
3  MidAtlantic Neonatal Associates, Morristown, New Jersey
› Author Affiliations
Further Information

Publication History

18 May 2020

21 May 2020

Publication Date:
13 June 2020 (online)

Abstract

Objective Since its emergence in late 2019, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), the novel coronavirus that causes novel coronavirus disease 2019 (COVID-19), has spread globally. Within the United States, some of the most affected regions have been New York, and Northern New Jersey. Our objective is to describe the impact of COVID-19 in a large delivery service in Northern New Jersey, including its effects on labor and delivery (L&D), the newborn nursery, and the neonatal intensive care unit (NICU).

Materials and Methods Between April 21, 2020 and May 5, 2020, a total of 78 mothers (3.6% of deliveries) were identified by screening history or examination to either be COVID-19 positive or possible positives (persons under investigation). Of the mothers who were tested after admission to L&D, 28% tested positive for SARS-CoV-2.

Discussion Isolation between mother and infant was recommended in 62 cases, either because the mother was positive for SARS-CoV-2 or because the test was still pending. Fifty-four families (87%) agreed to isolation and separation. The majority of infants, 51 (94%), were initially isolated on the newborn nursery. Six needed NICU admission. No infants had clinical evidence of symptomatic COVID-19 infection. Fourteen infants whose mothers were positive for SARS-CoV-2, and who had been separated from the mother at birth were tested for SARS-CoV-2 postnatally. All were negative.

Results COVID-19 posed a significant burden to mothers, infants, and staff over the 5-week study period. The yield from screening mothers for COVID-19 on L&D was high. Most families accepted the need for postnatal isolation and separation of mother and newborn.

Conclusion Our study suggests that the transmission of SARS-CoV-2 from mother to her fetus/newborn seems to be uncommon if appropriate separation measures are performed at birth.

Key Points

  • The yield of targeted testing for SARS-CoV-2, on mothers on Labor and Delivery is high.

  • Agreement to separation of mothers and infants to reduce transmission of SARS-CoV-2 was high.

  • The incidence of symptomatic COVID-19 in newborns is low, if appropriate separation occurs at birth.