Neonatal Resuscitation and Postresuscitation Care of Infants Born to Mothers with Suspected or Confirmed SARS-CoV-2 Infection

Praveen Chandrasekharan; Maximo Vento; Daniele Trevisanuto; Elizabeth Partridge; Mark A. Underwood; Jean Wiedeman; Anup Katheria; Satyan Lakshminrusimha

doi:10.1055/s-0040-1709688

American Journal of Perinatology, Table of Contents

Am J Perinatol 2020; 37(08): 813-824
DOI: 10.1055/s-0040-1709688

Clinical Opinion

Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Neonatal Resuscitation and Postresuscitation Care of Infants Born to Mothers with Suspected or Confirmed SARS-CoV-2 Infection

Praveen Chandrasekharan

¹Division of Neonatology, Department of Pediatrics, Oishei Children's Hospital of Buffalo, University at Buffalo, Buffalo, New York

,

Maximo Vento

²Division of Neonatology, University and Polytechnic Hospital La Fe, Valencia, Spain

,

Daniele Trevisanuto

³Department of Pediatrics, University-Hospital of Padova, Padova, Italy

,

Elizabeth Partridge

⁴Division of Infectious Disease, Department of Pediatrics, University of California, Davis, California

,

Mark A. Underwood

⁵Division of Neonatology, Department of Pediatrics, University of California, Davis, California

,

Jean Wiedeman

⁴Division of Infectious Disease, Department of Pediatrics, University of California, Davis, California

,

Anup Katheria

⁶Sharp Mary Birch Hospital for Women and Newborns, San Diego, California

,

Satyan Lakshminrusimha

⁵Division of Neonatology, Department of Pediatrics, University of California, Davis, California

› Author Affiliations

Abstract

The first case of novel coronavirus disease of 2019 (COVID-19) caused by severe acute respiratory syndrome–coronavirus 2 (SARS-CoV-2) was reported in November2019. The rapid progression to a global pandemic of COVID-19 has had profound medical, social, and economic consequences. Pregnant women and newborns represent a vulnerable population. However, the precise impact of this novel virus on the fetus and neonate remains uncertain. Appropriate protection of health care workers and newly born infants during and after delivery by a COVID-19 mother is essential. There is some disagreement among expert organizations on an optimal approach based on resource availability, surge volume, and potential risk of transmission. The manuscript outlines the precautions and steps to be taken before, during, and after resuscitation of a newborn born to a COVID-19 mother, including three optional variations of current standards involving shared-decision making with parents for perinatal management, resuscitation of the newborn, disposition, nutrition, and postdischarge care. The availability of resources may also drive the application of these guidelines. More evidence and research are needed to assess the risk of vertical and horizontal transmission of SARS-CoV-2 and its impact on fetal and neonatal outcomes.

Key Points

The risk of vertical transmission is unclear; transmission from family members/providers to neonates is possible.
Optimal personal-protective-equipment (airborne vs. droplet/contact precautions) for providers is crucial to prevent transmission.
Parents should be engaged in shared decision-making with options for rooming in, skin-to-skin contact, and breastfeeding.

Keywords

neonatal resuscitation - COVID-19 - novel coronavirus - SARS-CoV-2

Full Text

References

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