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CC BY-NC-ND 4.0 · SynOpen 2020; 04(02): 23-32
DOI: 10.1055/s-0040-1707105
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This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/) (2020) The Author(s)

Synthesis of 5-Fluoroaminobenzothiazoles

Pooja Sharma
a   Department of Chemistry, The University of The West Indies, St. Augustine, Trinidad and Tobago   eMail: gurdial.singh@sta.uwi.edu
,
Gurdial Singh  ∗
a   Department of Chemistry, The University of The West Indies, St. Augustine, Trinidad and Tobago   eMail: gurdial.singh@sta.uwi.edu
,
Bhoomendra A. Bhongade
a   Department of Chemistry, The University of The West Indies, St. Augustine, Trinidad and Tobago   eMail: gurdial.singh@sta.uwi.edu
b   RAK College of Pharmaceutical Sciences, RAK Medical & Health Sciences University, Ras Al Khaimah, UAE
,
Malleshappa N. Noolvi
c   Shree Dhanvantary Pharmacy College, Surat, Gujarat, India
,
Andanappa K. Gadad
d   School of Pharmacy, Faculty of Medical Sciences, The University of The West Indies, Mount Hope, Trinidad and Tobago
› InstitutsangabenWe thank to the government of Trinidad and Tobago and University of the West Indies for financial support.
Weitere Informationen

Publikationsverlauf

Received: 03. März 2020

Accepted after revision: 09. April 2020

Publikationsdatum:
11. Mai 2020 (online)

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Abstract

A series of 5-fluoro-2-(N-substituted)aminobenzothiazoles were synthesized by intramolecular cyclisation of the corresponding thioureas, which were prepared by treatment of 4-substituted 3-fluoroanilines with appropriate isothiocyanates.

Key words

synthetic methods - 2-aminobenzothiazoles - isothiocyanates - chiral - fluoro - heterocyclic

Supporting Information

    Supporting information for this article is available online at https://doi.org/10.1055/s-0040-1707105.
  • Supporting Information
 

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