A Randomised Controlled Trial Using Individualised Homeopathic Treatment for Modifying Anger and Blood Pressure in Patients with Essential Hypertension – Comparison Against Standard Care Treatment
05 February 2020 (online)
Background: Hypertension (HT) is the most pervasive disease worldwide, causing multiple chronic conditions without apparent symptoms. Global burden of disease is extremely high due to HT. The Framingham study tells us that about 90% of people after the age of 65 years have a lifetime risk of developing HT. The aetiology of hypertension is various and complex, involving both genetic and behavioural factors. More and more people experience increased anger, anxiety and depression brought on by globalization, cultural changes, socioeconomic changes, and stress at the work place. Anger is a critical contributing factor in essential hypertension (EHT). In our research, we tried to correlate anger with EHT and to treat anger – and thus the level of hypertension – with homeopathic simillimum.
To investigate the relationship between level of anger and level of hypertension.
To evaluate the safety and efficacy of homeopathic treatment on anger – and thereby on blood pressure (BP) – in comparison with standard care treatment for hypertension.
Methods: 300 patients with EHT were screened, 172 of whom (108 men, 64 women) were enrolled after informed, voluntary consent. They were divided into two equal groups by simple randomisation. After thorough case-taking, all patients were advised regarding DASH (Dietary Approaches to Stop Hypertension), life-style modification and anti-hypertensives, as per individual requirements. The STAXI-2 scale was applied to measure anger at the beginning and after six months’ study period. One group was kept on placebo and the other on individualised homeopathic medicine. Regular follow-up was every two weeks. Data generated was analysed by SPSS v.21.
Results: Except state anger and its components, all other variables of anger, as well as systolic and diastolic BP, were remarkably reduced (p < 0.001) by homeopathy. Also, 89% of patients in the homeopathy group experienced relief in the symptoms of co-morbidities such as diabetes mellitus, rheumatoid arthritis, psoriasis, gastro-esophageal reflux disorder and chronic obstructive pulmonary disorder. Standard care with anti-hypertensives had little impact on anger or the general psychopathology of patients, and had no effect on co-morbidities.
Conclusion: The patients treated with individualised homeopathic treatment showed statistically significant improvement in anger and hypertension, and also showed notable relief in the symptoms of co-morbidities.
Keywords: Essential hypertension, state anger, trait anger, STAXI-2