RSS-Feed abonnieren
DOI: 10.1055/s-0039-3402484
Perfil cardiovascular en pacientes con disfunción eréctil tratados en un centro de alta complejidad en la ciudad de Medellín, Colombia
Cardiovascular Profile in Patients with Erectile Dysfunction Treated in a High Complexity Center in Medellín City, ColombiaResumen
Objetivo Determinar el perfil cardiovascular de los pacientes con disfunción eréctil en un centro de alta complejidad de Medellín.
Métodos Estudio descriptivo, retrospectivo, en el que se incluyeron pacientes con diagnóstico de disfunción eréctil confirmado por el departamento de Urología, tratados en un centro de alta complejidad de Medellín entre 2010 y 2017; excluyendo aquellos con historia clínica con información incompleta o con desenlace cardiovascular previo al diagnóstico de disfunción eréctil. Los datos se obtuvieron de fuentes secundarias y se realizó su registro en una base de datos para su análisis mediante paquete estadístico (SPSS 24 Inc, Chicago, IL).
Resultados Se captaron, durante el periodo de estudio, 67 pacientes con disfunción eréctil que cumplieron los criterios de elegibilidad. Con una media de edad de 47,5 años. El 82% presentó disfunción eréctil severa, que estuvo asociada con el antecedente de angina, enfermedad coronaria y síndrome coronario agudo. Así mismo, más del 80% de los pacientes con diabetes, hipertensión, dislipidemia, tabaquismo, enfermedad renal crónica, obesidad y alcoholismo considerados como marcadores importantes de riesgo cardiovascular, presentaron disfunción eréctil severa.
Conclusión La comorbilidad cardiovascular en pacientes con DE es alta, existiendo una relación al compartir factores de riesgo y vías fisiopatológicas. Los pacientes con DE severa presentan mayor número de patologías asociadas, volviéndolos más propensos a desenlaces cardio-cerebrovasculares.
Abstract
Objective To determine the cardiovascular profile of patients with erectile dysfunction in a high complexity center in Medellín.
Methods Descriptive, retrospective study, in patients diagnosed with erectile dysfunction confirmed by the Department of Urology, treated in a high complexity center of Medellín between 2010 and 2017; excluding those with a clinical history with incomplete information or with a cardiovascular outcome prior to the diagnosis of erectile dysfunction. The data were obtained from secondary sources and their registration was made in a database for analysis by statistical package (SPSS 24 Inc, Chicago, IL).
Results 67 patients with erectile dysfunction were selected during the study period, who met the eligibility criteria. With an average age of 47.5 years. 82% had severe erectile dysfunction, and it was associated with a history of angina, coronary disease and acute coronary syndrome. Likewise, more than 80% of patients with diabetes, hypertension, dyslipidemia, smoking, chronic kidney disease, obesity and alcoholism, considered important markers of cardiovascular risk, presented severe erectile dysfunction.
Conclusion Cardiovascular comorbidity in patients with ED is high, there is a relationship, sharing risk factors and pathophysiological pathways. Patients with severe ED have a greater number of associated pathologies, making them more prone to cardio-cerebrovascular outcomes.
Palabras clave
disfunción eréctil - enfermedades cardiovasculares - enfermedad coronaria - angina de pecho - endotelioKeywords
erectile dysfunction - cardiovascular diseases - coronary disease - angina pectoris - endotheliumNota
La investigación se desarrolló en el Hospital Pablo Tobón Uribe Medellín, Colombia.
Publikationsverlauf
Eingereicht: 18. Juli 2019
Angenommen: 14. Oktober 2019
Artikel online veröffentlicht:
07. Februar 2020
© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Sociedad Colombiana de Urología. Publicado por Thieme Revinter Publicações Ltda
Rio de Janeiro, Brazil
-
Referencias
- 1 Demirkol S, Balta S, Kucuk U. , et al. Association between microvascular angina and erectile dsyfunction. Int J Impot Res 2014; 26 (04) 124-127
- 2 Katsiki N, Wierzbicki AS, Mikhailidis DP. Erectile dysfunction and coronary heart disease. Curr Opin Cardiol 2015; 30 (04) 416-421
- 3 Brock G. Diagnosing erectile dysfunction could save your patient's life. Can Urol Assoc J 2014; 8 (7-8, Suppl 5) S151-S152
- 4 Canat L, Canat M, Guner B, Gurbuz C, Caşkurlu T. Association between renal function, erectile function and coronary artery disease: detection with coronary angiography. Korean J Urol 2015; 56 (01) 76-81
- 5 Sanchez E, Pastuszak AW, Khera M. Erectile dysfunction, metabolic syndrome, and cardiovascular risks: facts and controversies. Transl Androl Urol 2017; 6 (01) 28-36
- 6 Ceballos MP, Álvarez Villarraga JD, Silva Herrera JM, Uribe JF, Mantilla D. Guía de disfunción eréctil. Sociedad Colombiana de Urología. Urol Colomb 2015; 24 (03) 185.e1-185.e22
- 7 Gazzaruso C, Giordanetti S, De Amici E. , et al. Relationship between erectile dysfunction and silent myocardial ischemia in apparently uncomplicated type 2 diabetic patients. Circulation 2004; 110 (01) 22-26
- 8 Wespes E, Amar E, Eardley I. , et al. Guía clínica sobre la disfunción sexual masculina: disfunción eréctil y eyaculación precoz. European Association of Urology; 2010: 843-900
- 9 Wespes E, Amar E, Hatzichristou D, Montorsi F, Pryor J, Vardi Y. European Association of Urology. Guidelines on erectile dysfunction. Eur Urol 2002; 41 (01) 1-5
- 10 Levine GN, Steinke EE, Bakaeen FG. , et al; American Heart Association Council on Clinical Cardiology, Council on Cardiovascular Nursing, Council on Cardiovascular Surgery and Anesthesia, Council on Quality of Care and Outcomes Research. Sexual activity and cardiovascular disease: a scientific statement from the American Heart Association. Circulation 2012; 125 (08) 1058-1072
- 11 Menezes A, Artham S, Lavie CJ, Milani RV, O'Keefe J. Erectile dysfunction and cardiovascular disease. Postgrad Med 2011; 123 (03) 7-16
- 12 Pastuszak AW, Hyman DA, Yadav N. , et al. Erectile dysfunction as a marker for cardiovascular disease diagnosis and intervention: a cost analysis. J Sex Med 2015; 12 (04) 975-984
- 13 Montorsi P, Ravagnani PM, Galli S. , et al. Association between erectile dysfunction and coronary artery disease. Role of coronary clinical presentation and extent of coronary vessels involvement: the COBRA trial. Eur Heart J 2006; 27 (22) 2632-2639
- 14 Nehra A, Jackson G, Miner M. , et al. The Princeton III Consensus recommendations for the management of erectile dysfunction and cardiovascular disease. Mayo Clin Proc 2012; 87 (08) 766-778
- 15 Mulhall JP, Goldstein I, Bushmakin AG, Cappelleri JC, Hvidsten K. Validation of the erection hardness score. J Sex Med 2007; 4 (06) 1626-1634
- 16 Enriquez DMB, Oyola KVL, Ruiz JEY. Cardiovascular Risk Factors and Diabetes in Medical Students: Observational Study. Exp Colomb 2018; 6 (02) 61-65
- 17 Feldman HA, Johannes CB, Derby CA. , et al. Erectile dysfunction and coronary risk factors: prospective results from the Massachusetts male aging study. Prev Med 2000; 30 (04) 328-338
- 18 Weber MF, Smith DP, O'Connell DL. , et al. Risk factors for erectile dysfunction in a cohort of 108 477 Australian men. Med J Aust 2013; 199 (02) 107-111
- 19 Meller SM, Stilp E, Walker CN, Mena-Hurtado C. The link between vasculogenic erectile dysfunction, coronary artery disease, and peripheral artery disease: role of metabolic factors and endovascular therapy. J Invasive Cardiol 2013; 25 (06) 313-319