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Am J Perinatol 2021; 38(07): 721-727
DOI: 10.1055/s-0039-3400983
Original Article

References Values of Fetal Heart Myocardial Volume by Three-Dimensional Ultrasound using Spatiotemporal Image Correlation and Virtual Organ Computer-Aided Analysis Methods and Their Applicability in Pregestational Diabetic Women

José Francisco Melo Júnior
1   Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil
,
Nathalie Jeanne Bravo-valenzuela
1   Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil
,
Luciano Marcondes Machado Nardozza
1   Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil
,
Alberto Borges Peixoto
1   Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil
2   Gynecology and Obstetrics Service, Mario Palmério University Hospital, University of Uberaba (UNIUBE), Uberaba, Brazil
,
Rosiane Mattar
1   Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil
,
Wellington P. Martins
3   Department of Reproductive Medicine, SEMEAR Fertilidade, Ribeirão Preto, Brazil
,
David Baptista da Silva Pares
1   Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil
,
Edward Araujo Júnior
1   Department of Obstetrics, Paulista School of Medicine, Federal University of São Paulo (EPM-UNIFESP), São Paulo, Brazil
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Abstract

Objective To determine reference values for myocardial volume of the fetal heart using three-dimensional ultrasound with spatiotemporal image correlation (STIC) and virtual organ computer-aided analysis (VOCAL) and to assess their applicability in women with pregestational diabetes.

Study Design This retrospective cross-sectional study included 177 normal pregnant women with fetuses between 200/7 and 336/7 weeks of age. Fetal cardiac volumes were collected using the STIC method, and myocardial volume was obtained by subtraction of the intracavitary volumes using the VOCAL 30-degree method. Intra- and interobserver reproducibility values were determined using the concordance correlation coefficient (CCC). Sixteen women with pregestational diabetes mellitus were evaluated for validation.

Results There was a strong correlation between fetal myocardial volume and gestational age (R 2 = 0.82). Intra- and interobserver reproducibility values were excellent and moderate, respectively, with CCCs of 0.99 and 0.83, respectively. There was no significant difference in mean fetal myocardial volume between normal pregnant women and those with pregestational diabetes (p = 0.64).

Conclusion Reference values for myocardial volume of the fetal heart were determined in normal pregnant women and were not statistically different from those in women with pregestational diabetes mellitus.

Keywords

fetal heart - myocardium - three-dimensional ultrasound - virtual organ computer-aided analysis - reference values - pregestational diabetes mellitus


Publication History

Received: 22 August 2019

Accepted: 24 October 2019

Article published online:
13 December 2019

© 2019. Thieme. All rights reserved.

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