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J Pediatr Intensive Care 2019; 08(04): 251-254
DOI: 10.1055/s-0039-1694991
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Transfusion-Associated Acute Lung Injury following Donor Granulocyte Transfusion in Two Pediatric Patients

Didar Arslan 
1   Department of Pediatric Intensive Care, Cukurova University Faculty of Medicine, Adana, Turkey
,
Dincer Yildizdas
1   Department of Pediatric Intensive Care, Cukurova University Faculty of Medicine, Adana, Turkey
,
Ozden Ozgur Horoz
1   Department of Pediatric Intensive Care, Cukurova University Faculty of Medicine, Adana, Turkey
,
Nagehan Aslan
1   Department of Pediatric Intensive Care, Cukurova University Faculty of Medicine, Adana, Turkey
,
Goksel Leblebisatan
2   Department of Pediatric Hematology, Çukurova University Faculty of Medicine, Adana, Turkey
› Author Affiliations
Further Information

Publication History

03 May 2019

06 July 2019

Publication Date:
26 August 2019 (online)

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Abstract

Transfusion-associated acute lung injury (TRALI) is one of the complications seen due to transfusion. Hypoxemia and bilateral pulmonary infiltration in posteroanterior chest roentgenogram is seen in all cases during transfusion or within the first 6 hours; fever, hypotension, and pink frothy bleeding from endotracheal tube may also be seen. It can be seen following the administration of any blood product. The management strategies for TRALI include withholding the transfusion, positive pressure breathing support, and diuretics. There are few reported cases of TRALI occurring following donor granulocyte transfusion (DGT). In this article, we discuss two cases of TRALI following DGT transfusion.

Keywords

pediatric - donor granulocyte transfusion - TRALI
 

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