J Neurol Surg B Skull Base 2019; 80(S 01): S1-S244
DOI: 10.1055/s-0039-1679760
Poster Presentations
Georg Thieme Verlag KG Stuttgart · New York

Skull Base Aspergillosis: 20 Years of Experience of More Than 200 Cases from a Tertiary Neurosciences Center

Sandeep Mohindra
1   Postgraduate Institute of Medical Education and Research, Chandigarh, India
,
Satyawati Mohindra
1   Postgraduate Institute of Medical Education and Research, Chandigarh, India
› Author Affiliations
Further Information

Publication History

Publication Date:
06 February 2019 (online)

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Since 1998, a total of 212 patients of pathologically proven aspergillosis of anterior/middle cranial floor were managed at our neurosciences center. We administered antifungal agents including Amphotericin B and Voriconazole to all of our cases. More than 80% of cases underwent endoscopic approach to establish pathology.

About 50% patients underwent anterior cranial fossa repair using pedicled pericranial grafts so as to disconnect rhinological source of spread of aspergillosis to intracranial compartment. Long-term outcome has improved significantly in later years and is not as nihilistic as previously assumed.