J Reconstr Microsurg 2019; 35(02): 090-096
DOI: 10.1055/s-0038-1667167
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Evaluating Venous Drainage in Reverse Flow Pedicles: Available Evidence and Mechanisms

Sarah Karinja
1  Columbia University College of Physicians and Surgeons, Columbia University, New York, New York, United States
,
Johanna Riesel
2  Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, United States
,
Matthew L. Iorio
3  Division of Plastic and Reconstructive Surgery, University of Colorado Anschutz Medical Center, University of Colorado, Aurora, Colorado, United States
› Author Affiliations
Further Information

Publication History

20 January 2018

22 May 2018

Publication Date:
29 July 2018 (online)

Abstract

Background The anatomy and physiology of venous drainage in the reversed flow vascular pedicle is controversial and there have been few well-designed, controlled studies to effectively evaluate the physiology. We evaluated the available evidence for venous drainage to synthesize the conclusions of these studies, and to identify areas in need of further research.

Methods Electronic databases were searched for articles published from January 1, 1950 to November 1, 2017. A total of 316 citations were screened for inclusion. Fifty articles met inclusion criteria and underwent review, yielding 12 articles for final data analysis. Three principal study types were found: human cadaveric (7), animal (3), human clinical (1), and mixed (1).

Results We identified two main theories regarding the mechanism of venous drainage in reverse flow flaps. The “avalvular bypass” theory is based on the findings of intact valves of the venae comitantes, and venous outflow through the crossover pattern of the communicating branches and bypass pattern of the collateral branches. Alternatively, the “valvular incompetence” theory implies that pedicle dissection, proximal ligation, and insetting of the flap cause physiologic changes, such as increased venous pressure, denervation, and simultaneous proximal and distal filling, which together result in valvular insufficiency.

Conclusion The mechanism by which retrograde venous outflow occurs in reverse flow flaps remains controversial. Nonetheless, a few well-designed studies have contributed to the understanding of venous anatomy and outflow. Most likely, the true mechanism is based on venous outflow that occurs via the “avalvular bypass” route initially and the “valvular incompetence” route later.

Disclosures

The authors did not receive any funding for this study. The authors have no financial interests in any of the products or techniques mentioned and have received no external support related to this study