Effect of Venous Stasis on Vessel Wall Fibrinolysis

Björn Stenberg; Anders Bylock; Bo Risberg

doi:10.1055/s-0038-1661067

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1984; 51(02): 240-242
DOI: 10.1055/s-0038-1661067

Original Article

Schattauer GmbH Stuttgart

Effect of Venous Stasis on Vessel Wall Fibrinolysis

Björn Stenberg

The Department of Surgery I and Arterial Biology Group, Sahlgrenska Sjukhuset, University of Göteborg, Sweden

,

Anders Bylock

The Department of Surgery I and Arterial Biology Group, Sahlgrenska Sjukhuset, University of Göteborg, Sweden

,

Bo Risberg

The Department of Surgery I and Arterial Biology Group, Sahlgrenska Sjukhuset, University of Göteborg, Sweden

› Author Affiliations

Abstract

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Summary

The effects of prolonged venous stasis on release of plasminogen activators (PA) from the caval vein of rats were studied.

PA activity was continuously reduced in the intimal layer and after 8 hr of stasis the reduction was statistically significant. After 2 and 3 days no intimal PA activity was found. The PA activity in the adventitial vasa vasorum was unchanged during the experimental period.

Keywords

Stasis - Endothelium - Fibrinolysis

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References

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