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Thromb Haemost 1985; 54(03): 617-618
DOI: 10.1055/s-0038-1660082
Original Article
Schattauer GmbH Stuttgart

Urokinase Antigen in Plasma of Patients with Liver Cirrhosis and Hepatoma

J C Kirchheimer
*   The Laboratory for Clinical Experimental Physiologiy, Department of Medical Physiology, University of Vienna, Austria
,
K Huber
**   The II. Department of Gastroenterology and Hepatology, University of Vienna, Austria
,
P Polterauer
**   The II. Department of Gastroenterology and Hepatology, University of Vienna, Austria
,
B R Binder
*   The Laboratory for Clinical Experimental Physiologiy, Department of Medical Physiology, University of Vienna, Austria
› Author Affiliations
Further Information

Publication History

Received 09 April 1985

Accepted 25 July 1985

Publication Date:
19 July 2018 (online)

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Summary

Plasma urokinase antigen levels were studied in 78 patients suffering from liver diseases. Blood was drawn before any specific medication was initiated. Impairment of liver function was comparable in all patients. In both groups of cirrhotic liver disease (alcoholic and non-alcoholic), normal levels of plasma urokinase antigen were found as compared to age-matched control groups. In both groups of patients with hepatomas (with or without a history of liver cirrhosis), however, significantly increased plasma urokinase antigen levels could be determined. These data indicate that an increase in plasma urokinase antigen might rather relate to malignant growth in liver disease than to impaired liver function.

Keywords

Urokinase antigen - Plasma prourokinase - Liver cirrhosis - Hepatoma
 

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