Thromb Haemost 1981; 46(04): 747-748
DOI: 10.1055/s-0038-1653467
Original Article
Schattauer GmbH Stuttgart

Prothrombin-Activator (Thromboplastin) Generation in the Blood of Water Snake (Natrix piscator)

V M Srivastava
The Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
,
B Dube
The Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
,
R K Dube
The Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
,
G P Agarwal
The Institute of Medical Sciences, Banaras Hindu University, Varanasi, India
› Author Affiliations
Further Information

Publication History

Received 01 July 1981

Accepted 26 October 1981

Publication Date:
05 July 2018 (online)

Summary

The generation of prothrombin-activator (thromboplastin) in water snake (Natrix piscator) is clearly delayed, Compared to a mammalian system, but the final activity is well comparable to that in man, when homologous sources of “phospholipid” (erythrocyte-lysate) and of substrate plasma are employed in one stage “thromboplastin generation test”. The use of heterologous source of either of the above reagents resulted in significantly longer clotting times; hence the need for homologous source of above reagents in the test is emphasized for comparative studies on animal haemostasis.