CC BY-NC-ND 4.0 · JCS 2018; 08(01): e27-e30
DOI: 10.1055/s-0038-1641601
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Transient Cerebral Vasculopathy: A Rare Complication Associated with Cerebral Gnathostomiasis

Vitchayaporn Emarach Saengow
1  Department of Pediatrics, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand
Oragarn Wongfukiat
2  Department of Radiology, Maharat Nakhon Ratchasima Hospital, Nakhon Ratchasima, Thailand
› Author Affiliations
Funding None.
Further Information

Publication History

30 November 2017

04 March 2018

Publication Date:
19 April 2018 (online)



Gnathostomiasis is a common parasitic infection in Southeast Asia, involving many organs in infected human hosts. Common neurological manifestations of Gnathostoma infection include radiculomyelitis, eosinophilic meningitis, and nontraumatic subarachnoid hemorrhage, leading to a high mortality and morbidity. This study first reported transient cerebral vasculopathy, an atypical neurological manifestation, in an 11-year-old Thai girl. The patient was diagnosed with intracerebral and intraventricular hemorrhage, and meningitis with atypical cerebrospinal fluid (CSF) profile. The imaging study of the brain revealed the abnormal white matter lesion and transient cerebral vasculopathy with the cerebral hemorrhage showing a track-like appearance (at the level of the corpus callosum). The serological testing in CSF and serum using the enzyme-linked immunosorbent assay (ELISA) technique was positive for Gnathostoma spinigerum. The patient spontaneously recovered within 3 months without albendazole or corticosteroid treatments.